Results 121 to 130 of about 11,653,432 (296)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Zhileng xuebaoGiven that measurements made under steady-state laboratory conditions cannot fully reflect the actual performance of air conditioners， the dynamic measurement of room air conditioner performance based on virtual buildings has become a research hotspot ...
Gao Yuping +7 more
doaj
Commonwealth Bank Building, Brisbane Street, Launceston [picture] /
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892262 ...
Key, Mike, 1951-
core
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Old Toll House, Rocks Road on Derwent River, New Norfolk [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
St Peter's Catholic Church. Hillside Crescent, New Norfolk [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892270 ...
Key, Mike, 1951-
core
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Hunters Hotel, Orr Street, Queenstown. Built late 1800s [picture].
, 1995 Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic-an11892265 ...
Key, Mike, 1951-
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source