Results 91 to 100 of about 1,421,153 (287)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Pre-conceptual-schema-based patterns for deriving key performance indicators from strategic objectives

open access: yesIngeniería e Investigación, 2017
Performance measurement is crucial for achieving business success. Moreover, such success is also related to the fulfillment of the organizational strategic objectives.
Carlos Mario Zapata Jaramillo   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

UK Economic Performance Since 1997: Growth, Productivity and Jobs [PDF]

open access: yes
A common view is that the performance of the UK economy between 1997 and 2010 under Labour was very weak and that the current economic problems are a consequence of poor policies in this period.
Anna Valero, Dan Corry, John Van Reenen
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

How Do You Become a Reflective Professional? [PDF]

open access: yes, 2011
The standards reflect a model of professional accountability but also of professional excellence. Teachers often face tensions between the ‘professional artistry’ of their role and the more technical aspects associated with exam results as a key ...
Griggs, G., Thomas, Lorraine
core   +1 more source

Supporting UAV Cellular Communications through Massive MIMO

open access: yes, 2018
In this article, we provide a much-needed study of UAV cellular communications, focusing on the rates achievable for the UAV downlink command and control (C&C) channel.
Björnson, Emil   +4 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Optimizing the performance appraisal system of coal enterprises in the context of"dual carbon"

open access: yes矿业科学学报
Performance appraisal is an important means to assess employees' work performance. It serves to enhance the production competence of frontline employees through feedback in order to promote green and low-carbon development of coal enterprises.
QI Peng, SUN Xiaoru
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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