Results 141 to 150 of about 14,643,332 (274)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Performance indicators in community health: development of a process. Final project report.

, 2002
Working Group members include: Lyndall Fowler, Haeather Gale, Joanne Gell, Peter Higgins, Kate Humphries, Gwyn Jolley, Angela Littleford, Alan Lohf, Penny Markham, Raven North, Pat Pearson, Santi Reeves, Diedre Searcy, Clare Shuttleworth, Chris ...
Performance Indicators in Community Health Project Working Group
core  

A framework for population health observatory from a global perspective: proposed preliminary maturity model and key performance indicators. [PDF]

Front Public Health
AlEissa MM, Alomary SA, Assiri AM.
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Higher Education Outcomes, Graduate Employment and University Performance Indicators [PDF]

Official employment-related Performance Indicators in UK Higher Education are based on the population of students responding to the First Destination Supplement (FDS).
Bratti, Massimiliano, McKnight, Abigail, Smith, Jeremy, Naylor, Robin   +3 more
core  

Strategic Key Performance Indicators for AI in Lead Optimization. [PDF]

ChemMedChem
Theis T, Flohr S, Binch H, Czechtizky W, Chudyk E, Klein M, Krier M, von Nussbaum F.   +7 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Mapping of key performance indicators for palliative care in intensive care settings: A scoping review protocol. [PDF]

HRB Open Res
King Y, May P, Brady AM.
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Modelling Key Performance Indicators (KPIs) in the Optimisation of Nanoimprint Lithography (NIL) Processes. [PDF]

Micromachines (Basel)
Pacana A, Czerwińska K.
europepmc   +1 more source