Results 91 to 100 of about 10,030,622 (339)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Combinatorial Penalties: Which structures are preserved by convex relaxations? [PDF]
, 2017 We consider the homogeneous and the non-homogeneous convex relaxations for combinatorial penalty functions defined on support sets. Our study identifies key differences in the tightness of the resulting relaxations through the notion of the lower ...
Bach, Francis +2 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Escrow mechanism for personal security keys on IBE
Tongxin xuebao, 2009 A new escrow mechanism for personal security keys on IBE was proposed.This mechanism constructed a security trust system composed of private key generator, key management center, and user security component to set up a personal security key escrow model,
ZOU Yue-peng1 +3 more
doaj
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Scientific ReportsTo mitigate problems such as injection water channeling, abrupt water breakthrough, rapid decline in oil production accompanied by an abrupt rise in water cut, and poor mobilization of matrix oil that commonly arise in low-permeability fractured ...
Shize Yin +3 more
doaj +1 more source
Key Backup and Recovery for Resilient DID Environment
MathematicsThis paper delves into the advantages of authentication algorithms employing self-sovereign identity, highlighting a reduced communication overhead and the elimination of single points of failure.
Jihwan Kim +3 more
doaj +1 more source
Rebuilding Household Wealth: Implications for Economic Recovery [PDF]
, 2013 [Excerpt] Congress was an active participant in the policy responses to the 2007-2009 recession and its aftermath and has an ongoing interest in macro-economic conditions.
Elwell, Craig K
core +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The effect of temperature on pyrolysis products during oil shale thermal decomposition
Scientific ReportsThis study systematically investigates the effect of temperature on product distribution and reaction mechanisms during the pyrolysis of oil shale through thermogravimetric analysis (TG) and fixed-bed pyrolysis experiments.
Fajun Zhao +5 more
doaj +1 more source