Results 131 to 140 of about 19,120,707 (376)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Particle Size as a Key Driver of Black Carbon Wet Removal: Advances and Insights

open access: yesAtmosphere
Black carbon (BC), as a potent light-absorbing aerosol, is mainly removed from the atmosphere through wet deposition. The efficiency of this process depends on the capacity of BC particles to serve as cloud condensation nuclei (CCN) or ice nuclei (IN ...
Yumeng Qiao   +3 more
doaj   +1 more source

Sample size calculation for estimating key epidemiological parameters using serological data and mathematical modelling [PDF]

open access: gold, 2018
Stéphanie Blaizot   +5 more
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Selecting Cryptographic Key Sizes [PDF]

open access: yes, 2000
Arjen K. Lenstra, Eric R. Verheul
openaire   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Efficient Non-malleable Codes and Key-Derivation for Poly-size Tampering Circuits [PDF]

open access: bronze, 2014
Sebastian Faust   +3 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

FGPointKAN++ point cloud segmentation and adaptive key cutting plane recognition for cow body size measurement

open access: yesArtificial Intelligence in Agriculture
Accurate and efficient body size measurement is essential for health assessment and production management in modern animal husbandry. In order to realize the segmentation of the point clouds at the pixel-level and the accurate calculation of body size ...
Guoyuan Zhou   +6 more
doaj   +1 more source

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