Results 201 to 210 of about 7,526,383 (337)

Grain shape in rice: a Genome-wide association study of the effector genes. [PDF]

BMC Plant Biol
Wang N, Hassan MA, Li K, Zhou K, Gan Q, Xia J, Lin C, Li Z, Ni D, Song F.   +9 more
europepmc   +1 more source

Application of a Pheromone-Based Bees Algorithm for Simultaneous Optimisation of Key Component Sizes and Control Strategy for Hybrid Electric Vehicles

, 2015
Long Vt
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Population-based variance-reduced evolution over stochastic landscapes. [PDF]

Sci Rep
Pei Z, He X, Pan Y, Peng B, Chen W, Zhou Y.   +5 more
europepmc   +1 more source

The uptake of population size estimation studies for key populations in guiding HIV responses on the African continent

, 2020
Nikita Viswasam, Carrie Lyons, Jack MacAllister, Gregorio A. Millett, Jennifer Sherwood, Amrita Rao, Stefan Baral   +6 more
openalex   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Real-Time Detection of Urban Atmospheric Micro-Nanoplastics and Their Chemical Mixing State Using Bioaerosol Single-Particle Mass Spectrometry. [PDF]

Environ Sci Technol
Zhang C, Qin Y, Li L, Aruffo E, Li S, Li X, Zhang N, Wu Y, Li H, Zhang Y, Dai Y, Wang M, Ge X, Li K, Du W, Cheng C, Li M, Chen M, Wang J.   +18 more
europepmc   +1 more source

Birth mass is the key to understanding the negative correlation between lifespan and body size in dogs

, 2016
Rong Fan, Gayla R. Olbricht, Xavior Baker, Chen Hou   +3 more
openalex   +1 more source

The impact of school sixth form size on educational attainment of pupils at Key Stage 5: 23 November 2016 [PDF]

, 2016
Foreman-Peck, James
core  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source