Results 251 to 260 of about 6,561,343 (302)

A key malignant switch in skin SCC

Nature Cancer, 2021
The mechanisms regulating the progression of benign tumors to malignant carcinomas remain incompletely understood. A new study identifies the transcription factor NR2F2 as a specific regulator of this transition that plays critical roles in the maintenance of the malignant tumor state.
Hui Yi Grace Lim, Nick Barker
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Secure Keyed Hashing on Programmable Switches

Proceedings of the ACM SIGCOMM 2021 Workshop on Secure Programmable network INfrastructure, 2021
Cyclic Redundancy Check (CRC) is a computationally inexpensive function readily available in many high-speed networking devices, and thus it is used extensively as a hash function in many data-plane applications. However, CRC is not a true cryptographic hash function, and it leaves applications vulnerable to attack.
Sophia Yoo, Xiaoqi Chen
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Loss of Gas7 Is a Key Metastatic Switch in Neuroblastoma

Cancer Research, 2021
Abstract Metastatic spread to distant tissues and organs is responsible for most cancer-related mortalities. Changes in the invasiveness ability of metastatic tumor cells often come with significantly altered gene expression profiles compared with primary tumor cells. Identifying the main actors involved in the metastatic switch of tumor
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CX3CL1: a key switch of cell death immunogenicity

Trends in Cancer
CX3CL1 (fractalkine) is a unique chemokine with dual roles in cancer biology, capable of exerting both tumor-promoting and tumor-suppressive effects. Acting through its receptor CX3CR1, CX3CL1 facilitates immune evasion, angiogenesis, metastasis, and tumor cell survival and proliferation by recruiting immunosuppressive myeloid-derived suppressor cells.
Robin Demuynck, Faye Naessens, Dmitri V. Krysko   +2 more
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Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch

Nature Genetics, 2006
The epidermis is a highly organized structure, the integrity of which is central to the protection of an organism. Development and subsequent maintenance of this tissue depends critically on the intricate balance between proliferation and differentiation of a resident stem cell population; however, the signals controlling the proliferation ...
Richardson, Rebecca J, Dixon, Jill, Malhotra, Saimon, Hardman, Matthew J, Knowles, Lynnette, Boot-Handford, Ray P, Shore, Paul, Whitmarsh, Alan, Dixon, Michael J   +8 more
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Switching elements, the key to FPGA architecture

Proceedings of WESCON '94, 2002
The architectural characteristics of FPGAs lie deep in their switching elements. Everything from the choice of logic blocks to the routing segmentation is influenced by these switches. SRAM switches provide the possibility of reprogramming the device. However, this feature comes at a prohibitive price: large area and reduced performance.
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Packet switching matrix: a key element for the backbone and the metro

IEEE Journal on Selected Areas in Communications, 2003
The evolution of the traffic in terms of volume and profile creates a need for multi-Terabit network elements providing the required flexibility to support a bit rate more and more variable than fix. In this paper, we describe an optical matrix that can be used in different network applications.
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