Results 31 to 40 of about 2,208 (170)

High-elevation adaptation and gestational hypoxia jointly shape vascular development in a rodent placenta. [PDF]

J Physiol
Abstract figure legend We investigated how environmental hypoxia and genetic adaptation to high altitudes jointly impact the development of the placental exchange surface in ways that might protect fetal growth potential. We used wild‐derived, lab‐born North American deer mice (Peromyscus maniculatus) from low‐elevation and high‐elevation environments (
Wilsterman K, Cheviron ZA, Good JM, Gurnoe-Brantley K, Jewett KE, Kiel K, Larson AM.   +6 more
europepmc   +2 more sources

The Caenorhabditis elegans JNK signaling pathway activates expression of stress response genes by derepressing the Fos/HDAC repressor complex. [PDF]

PLoS Genetics, 2013
MAP kinases are integral to the mechanisms by which cells respond to a wide variety of environmental stresses. In Caenorhabditis elegans, the KGB-1 JNK signaling pathway regulates the response to heavy metal stress.
Ayuna Hattori, Tomoaki Mizuno, Mayuko Akamatsu, Naoki Hisamoto, Kunihiro Matsumoto   +4 more
doaj   +1 more source

A Data‐Driven Threshold for Extreme Hyponatremia in the Emergency Department and Its Association With 28‐Day Mortality

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hyponatremia is a common electrolyte disorder in the emergency department (ED), but its clinical burden is not evenly distributed across the sodium spectrum. We conducted a retrospective observational cohort study of adult ED encounters at a tertiary referral hospital between July 2019 and July 2024 to identify a data‐driven threshold for ...
Yalcin Golcuk, Ömer‐Faruk Karakoyun, Fulden Cantaş‐Türkiş, İsmail Kırlı, Satuk‐Buğra Yıldırım, Bekir Baran, Burcu Kaymak‐Golcuk   +6 more
wiley   +1 more source

Evolutionary Dynamic Multiobjective Optimisation Assisted by Inverse Regression Tree Predictor

CAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Dynamic multiobjective optimisation problems (DMOPs) are optimisation problems with multiple conflicting objectives that can change over time. Most dynamic multiobjective optimisation evolutionary algorithms (DMOEAs) attempt to estimate Pareto‐optimal sets (PS) directly in the decision space.
Kai Gao, Lihong Xu
wiley   +1 more source

State of the Field: Scientific Internationalism during the Cold War

History, EarlyView.
ABSTRACT This article offers a state‐of‐the‐field assessment of the historiography of scientific internationalism during the Cold War, focusing on three connected problems: the reconceptualization of science diplomacy, the emergence of ‘techno‐dissent’ and the ethical turn in the history of science and technology.
Doubravka Olšáková
wiley   +1 more source

Spectacle and Spy Stories: The 1954 Royal Commission on Espionage

Australian Journal of Politics &History, EarlyView.
ABSTRACT The Menzies government's 1954 royal commission, established to investigate Soviet espionage in Australia, is well known as the backdrop to the Labor Party split. It saw opposition leader H.V. Evatt's demise and ushered in an almost 20‐year period of Liberal Party governance.
Ebony Nilsson
wiley   +1 more source

NMDA receptor subunit‐dependent analysis of radiprodil inhibition in neonatal male rat substantia nigra dopaminergic neurons

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Radiprodil is a GluN2B subunit selective NMDA receptor negative allosteric modulator which is currently under clinical investigation as a possible anti‐epileptic drug for paediatric use. Our goal was to investigate the inhibition of dopaminergic neuron NMDA responses by radiprodil.
Bangyuan Liu, Alasdair J. Gibb
wiley   +1 more source

Behaviour Support in Dentistry Core Outcomes (BeSiDe‐CO): A Core Outcome Set Development Study

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To develop a Core Outcome Set suitable for adults and children for use in studies of Dental Behaviour Support (DBS) techniques, including non‐pharmacological DBS, sedation and General Anaesthesia research. Methods Two systematic reviews generated a preliminary list of candidate outcomes that were shared with Key Stakeholders (KSG ...
Caoimhin Mac Giolla Phadraig, Isabel C. Olegário, Shaelynn Hsu, Maryam Al Zayer, Aisyah Binti Ahmad Fisal, Alison Dougall, Gareth B. Kitchen, Henry F. Duncan, Sarah Baker, Sharat Pani, Sreekanth Kumar Mallineni, Mandy Daly, The BeSiDe COS Collaboration, Tracey Scott, Carolyn Akintola, Éilish Burke, Steve Moore, Barbara Vallo, Jacobo Posse Limerese, Karin Alexandra Van Nes, Maiken Bagger, Olive Healy, Andrew Geddis‐Regan   +22 more
wiley   +1 more source

Advances in 4D Representation: Geometry, Motion, and Interaction

Computer Graphics Forum, EarlyView.
We survey 4D representation through three key pillars — geometry, motion, and interaction — offering a selective, representation‐centric perspective to guide researchers in choosing and customizing the right 4D representation for their tasks. Abstract We present a survey on 4D generation and reconstruction, a fast‐evolving subfield of computer graphics
M. Zhao, S. Nag, K. Wang, A. Vora, G. Ji, P. Chun, A. Mahdavi‐Amiri, H. Zhang   +7 more
wiley   +1 more source

Relationship of Latvian communist party and Latvian SSR KGB (1954–1991)

Genocidas ir Rezistencija, 2006
The Latvian Communist Party (LKP) and the Latvian KGB were the most important institutions controlling Latvian society throughout the communist occupation.
Ritvars Jansons
doaj   +1 more source