Results 181 to 190 of about 831,855 (280)

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

Advanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen, Rong Chen, Wei Li, Bin Song, Ruiying Zhang, Lewei Dai, Yuwei Qi, Ruqian Chen, Yifan Xu, Hangbin Li, Jingyi Huang, Fangping Wu, Jianan Peng, Xinyu Wang, Yang Xiong, Chaofeng Mu, Guilin Cheng, Zhaoshen Li, Shanming Ruan, Lei Huang, Mancang Gu   +20 more
wiley   +1 more source

Amiloride mitigates respiratory distress caused by WFDC2 deficiency via inhibiting the epithelial sodium channel. [PDF]

Nat Commun
Roh JW, Seo SK, Oh J, Kim SJ, Hong JW, Ohk J, Shim HS, Cho HJ, Woo A, Kim SY, Kang YA, Jung H, Kim KW, Park MS, Gee HY.   +14 more
europepmc   +1 more source

Ki Lal ? Ki Lal? in Spanish

Translation Today, 2019
openaire   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Clinicopathological Implications of IDH1 Mutation and Ki-67 Expression Across WHO Grades of Gliomas: Insights from a Prospective Observational Study. [PDF]

Iran J Pathol
Sinha K, Iyengar S, Bhushan R, Sharma A.
europepmc   +1 more source

Terminologie in der KI - KI in der Terminologie

Akten des Symposions Worms, 27.-29.
Drewer, Petra (Ed.), Mayer, Felix (Ed.), Pulitano, Donatella (Ed.)   +2 more
openaire   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

The establishment of prostate-specific, SKP2 humanized mice by CRISPR knock-in method reveals neoplastic initiation and microenvironmental reprogramming. [PDF]

Oncogene
Song L, Song Y, Nguyen V, Xu S, Ho K, Mohammed A, Shoemaker RH, Hoang BH, Yu J, Uchio E, Zi X.   +10 more
europepmc   +1 more source

To・ki・me・ki

, 1999
openaire   +1 more source

Der St.Galler KI-Kompetenzrahmen als Orientierung für Hochschullehre

Es gibt inzwischen zahlreiche Modelle und Frameworks zu KI-Kompetenzen, die jedoch oft sehr breit angelegt sind und damit nur begrenzt Orientierung für konkrete Bildungsbereiche bieten. Der St.
Bass, Steve, Schallert-Vallaster, Stefanie, Buchner, Josef   +2 more
core