Results 31 to 40 of about 930,181 (282)

Distribution of high- and low-risk human papillomavirus genotypes and their prophylactic vaccination coverage among West African women: systematic review

Journal of the Egyptian National Cancer Institute, 2023
Introduction The second most deadly gynecological cancer worldwide, cervical cancer is steadily on the rise in sub-Saharan Africa, while vaccination programs are struggling to get off the ground.
Rogomenoma Alice Ouedraogo, Ali Kande, Wendyam Marie Christelle Nadembega, Djeneba Ouermi, Théodora Mahoukèdè Zohoncon, Florencia Wendkuuni Djigma, Charlemagne Marie Ragnag-Newende Ouedraogo, Olga Mélanie Lompo, Jacques Simpore   +8 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Results of an early second PCR test performed on SARS-CoV-2 positive patients may support risk assessment for severe COVID-19

Scientific Reports, 2021
Identifying patients at increased risk for severe COVID-19 is of high priority during the pandemic as it could affect clinical management and shape public health guidelines.
Barak Mizrahi, Maytal Bivas-Benita, Nir Kalkstein, Pinchas Akiva, Chen Yanover, Yoav Yehezkelli, Yoav Kessler, Sharon Hermoni Alon, Eitan Rubin, Gabriel Chodick   +9 more
doaj   +1 more source

Von Kühlschranklichtern, KI-Pubertät und Turnschuhen. Thomas Metzinger im Gespräch mit Karsten Wendland. Transkript zum Podcast [PDF]

, 2021
Für den Philosophen Prof. Dr. Thomas Metzinger von der Universität Mainz ist es keineswegs ausgeschlossen, dass Künstliche Intelligenz irgendwann Bewusstsein haben könnte.
Lahn, Nadine, Wendland, Karsten, Vetter, Pascal   +2 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Increased rates of unattained developmental milestones among Israeli children between 2016 and 2020: a national report

Israel Journal of Health Policy Research, 2023
Background The early years of children’s lives are critical for their healthy development. Although children’s growth and development rates may vary, a significant delay during early childhood could indicate a medical or a developmental disorder ...
Irena Girshovitz, Guy Amit, Inbal Goldshtein, Deena R. Zimmerman, Ravit Baruch, Pinchas Akiva, Meytal Avgil Tsadok, Yair Sadaka   +7 more
doaj   +1 more source

Die Gründerväter der KI machten sich über Bewusstsein keine Gedanken. Christian Vater im Gespräch mit Karsten Wendland. Transkript zum Podcast [PDF]

, 2021
Für den Technikhistoriker Christian Vater, der in Heidelberg und Karlsruhe forscht, hat Forschung zu KI archäologische Qualitäten. Er gräbt Fundstü-cke aus, die unser heutiges Verständnis von KI prägen, auch wenn sie zu ihrer Zeit anders gemeint waren ...
Lahn, Nadine, Wendland, Karsten, Vetter, Pascal   +2 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

smartCasaplus – ein risikobasiertes geriatrisches Gesundheitscoaching für multimorbide Versicherte

Monitor Versorgungsforschung
Das geriatrische Schulungsprogramm Casaplus der MedicalContact AG bietet bereits seit 2007 telefonische Gesundheitscoachings für multimorbide geriatrische Versicherte, von dem bereits ca. 30.000 Versicherte profitiert haben.
Stephan Burger, Markus M. Müller, Thomas P. Zahn   +2 more
doaj   +1 more source