Results 11 to 20 of about 356,718 (243)

To Ki or Not to Ki: Re-Evaluating the Use and Potentials of Ki-67 for T Cell Analysis [PDF]

Frontiers in Immunology, 2021
This study discusses substantive advances in T cell proliferation analysis, with the aim to provoke a re-evaluation of the generally-held view that Ki-67 is a reliable proliferation markerper se, and to offer a more sensitive and effective method for T cell cycle analysis, with informative examples in mouse and human settings.
Francesca Di Rosa, Andrea Cossarizza, Andrea Cossarizza, Adrian C. Hayday, Adrian C. Hayday, Adrian C. Hayday   +5 more
openaire   +6 more sources

Carriage of mutations R462Q (rs 486907) and D541E (rs 627928) of the RNASEL gene and risk factors in patients with prostate cancer in Burkina Faso

BMC Medical Genomics, 2022
Background Prostate cancer (Pca) is a public health problem that affects men, usually of middle age or older. It is the second most common cancer diagnosed in men and the fifth leading cause of death.
Essonan Kadanga, Abdou Azaque Zouré, Théodora M. Zohoncon, Lassina Traoré, Bienvenu Désiré Ky, Albert Théophane Yonli, Djé Djénèba Aïda Traoré, Bapio Valery Jean Télesphore Elvira Bazié, Herman Karim Sombié, Pegdwendé Abel Sorgho, Sessi Frida Appoline Tovo, Kalifou Traoré, Teega-Wendé Clarisse Ouedraogo, Florencia W. Djigma, Jacques Simpore   +14 more
doaj   +1 more source

An Analysis of Factors Associated with Drug Use in Schools in The City of Ouagadougou in 2019

International Journal of Multidisciplinary Educational Research and Innovation, 2023
Faced with this situation, a general awareness has led to the creation of an international day against drug abuse and trafficking on June 26. Several international and regional conventions are working together to develop strategies and policies to fight ...
Cheick B. El F. Baga, Ludmila Akoyi, Hermine Tognon, Constant Paré Boyo, Jill Johns, Toé S. A. Josué, Nicolas Meda   +6 more
doaj   +1 more source

Validation of the Remote Automated ki:e Speech Biomarker for Cognition in Mild Cognitive Impairment: Verification and Validation following DiME V3 Framework

Digital Biomarkers, 2022
Introduction: Progressive cognitive decline is the cardinal behavioral symptom in most dementia-causing diseases such as Alzheimer’s disease. While most well-established measures for cognition might not fit tomorrow’s decentralized remote clinical trials,
Johannes Tröger, Ebru Baykara, Jian Zhao, Daphne ter Huurne, Nina Possemis, Elisa Mallick, Simona Schäfer, Louisa Schwed, Mario Mina, Nicklas Linz, Inez Ramakers, Craig Ritchie   +11 more
doaj   +1 more source

Agentivité reproductive, utilisation de la contraception et expérience des rapports sexuels non souhaités chez les femmes burkinabè [PDF]

Pensées Genre, Penser Autrement
Cette étude analyse les liens entre l’agentivité reproductive des femmes et deux résultats de santé reproductive au Burkina Faso : l’utilisation d’une méthode contraceptive moderne et l’expérience de rapports sexuels non souhaités.
Fiacre BAZIE, Yentéma ONADJA, Abdramane B. SOURA , Georges GUIELLA   +3 more
doaj   +1 more source

Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A

Neurobiology of Disease, 2008
The down-regulation of protein phosphatase 2A (PP2A) activity is thought to play an important role in the formation of tau hyperphosphorylation in the Alzheimer's disease (AD) brain. Methylation of the PP2A catalytic subunit at the L309 site can potently
Xin-Wen Zhou, Jan-Åke Gustafsson, Heikki Tanila, Cecilia Bjorkdahl, Rong Liu, Bengt Winblad, Jin-Jing Pei   +6 more
doaj   +1 more source

Potassium Iodide in Dermatology- Recent Advances in Mechanism of Action, Preparation, Uses and Adverse Effects

Indian Journal of Dermatology
Potassium iodide (KI) is a simple yet versatile drug. It has been successfully used for the treatment of various diseases in dermatology, but there are very limited studies on the exact mechanism of action, preparation, and dosage of potassium iodide ...
Nishant Goel, Bhavana R. Doshi
doaj   +1 more source

Increased rates of unattained developmental milestones among Israeli children between 2016 and 2020: a national report

Israel Journal of Health Policy Research, 2023
Background The early years of children’s lives are critical for their healthy development. Although children’s growth and development rates may vary, a significant delay during early childhood could indicate a medical or a developmental disorder ...
Irena Girshovitz, Guy Amit, Inbal Goldshtein, Deena R. Zimmerman, Ravit Baruch, Pinchas Akiva, Meytal Avgil Tsadok, Yair Sadaka   +7 more
doaj   +1 more source

Results of an early second PCR test performed on SARS-CoV-2 positive patients may support risk assessment for severe COVID-19

Scientific Reports, 2021
Identifying patients at increased risk for severe COVID-19 is of high priority during the pandemic as it could affect clinical management and shape public health guidelines.
Barak Mizrahi, Maytal Bivas-Benita, Nir Kalkstein, Pinchas Akiva, Chen Yanover, Yoav Yehezkelli, Yoav Kessler, Sharon Hermoni Alon, Eitan Rubin, Gabriel Chodick   +9 more
doaj   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna, Alexia Muresan, Estelle Lecluze, Karine Leduc, Nathalie Fournier, Maria Tamer, Jean‐François Delisle, Jeremi Charbonneau, Annie Viau, Jessica Darilus, Marie‐Joëlle Doré‐Bergeron, Valérie Arsenault, Evelyne Doyon‐Trottier, Stéphanie Forte, Nancy Robitaille, Yves Pastore, Thomas Pincez   +16 more
wiley   +1 more source