Results 11 to 20 of about 13,595,196 (243)

Vitamin D and endothelial function in chronic kidney disease [PDF]

open access: yes, 2014
PhDVitamin D deficiency in patients with chronic kidney disease, measured by reduced serum concentrations of 25 hydroxy vitamin D, is highly prevalent and associated with both endothelial dysfunction and an increased risk of cardiovascular disease ...
Dreyer, Gavin
core   +4 more sources

Iron deficiency after kidney transplantation [PDF]

open access: yes, 2021
Iron deficiency (ID) is highly prevalent in kidney transplant recipients (KTRs) and has been independently associated with an excess mortality risk in this population. Several causes lead to ID in KTRs, including inflammation, medication and an increased
Francke, Marith I.   +11 more
core   +3 more sources

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency. [PDF]

open access: yesAdv Sci (Weinh)
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Yang Q   +11 more
europepmc   +2 more sources

Moxibustion plus acupuncture improves the efficacy and quality of life of patients with polycystic ovary syndrome: A randomized controlled trial

open access: yesJournal of Integrative Nursing, 2021
Objective: To observe the effect of moxibustion combined with acupuncture on the efficacy and quality of life of spleen-kidney-yang-deficiency patients with polycystic ovary syndrome (PCOS).
Qian Zhang, Li-xiu Liu
doaj   +1 more source

Hypertension in mice lacking 11beta-hydroxysteroid dehydrogenase type 2 [PDF]

open access: yes, 1999
Deficiency of 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) in humans leads to the syndrome of apparent mineralocorticoid excess (SAME), in which cortisol illicitly occupies mineralocorticoid receptors, causing sodium retention, hypokalemia ...
Mullins, A J   +18 more
core   +1 more source

New susceptibility Loci associated with kidney disease in type 1 diabetes [PDF]

open access: yes, 2012
Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation.
Benjamin J. Keller (135013)   +597 more
core   +1 more source

Molecular basis and functional characterization of human 3-methylcrotonyl-CoA carboxylase deficiency [PDF]

open access: yes, 2009
3-Methylcrotonyl-CoA carboxylase (MCC) deficiency is a rare disorder of leucine catabolism inherited as an autosomal recessive trait. The phenotypic expression of the disease is highly variable, ranging from neonatal onset with severe neurological ...
Dantas, Maria Fernanda
core   +1 more source

Efficacy of Xiaozhoutian fire dragon moxibustion combined with traditional Chinese medicine on polycystic ovary syndrome with kidney yang deficiency: A randomized controlled trial [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo
Introduction/Objective. To investigate the efficacy of Xiaozhoutian fire dragon moxibustion combined with traditional Chinese medicine on polycystic ovary syndrome (PCOS) with kidney yang deficiency. Methods.
Yu Liuxiu   +7 more
doaj   +1 more source

Impact of Vitamin D Supplementation on Arterial Vasomotion, Stiffness and Endothelial Biomarkers in Chronic Kidney Disease Patients [PDF]

open access: yes, 2014
Background: Cardiovascular events are frequent and vascular endothelial function is abnormal in patients with chronic kidney disease (CKD). We demonstrated endothelial dysfunction with vitamin D deficiency in CKD patients; however the impact of ...
Chitalia, N   +31 more
core   +1 more source

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis [PDF]

open access: yes, 2014
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Schroeder, N   +6 more
core   +1 more source

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