Results 191 to 200 of about 2,352,989 (309)

GaSex Nanoparticles Modulate Neutrophil Function and Mitigate NET‐Driven Osteogenic Impairment in Osteomyelitis Therapy

open access: yesAdvanced Materials, EarlyView.
Neutrophil extracellular traps (NETs) emerge as a critical repair‐limiting factor in osteomyelitis, driving osteoblast mitochondrial dysfunction and excessive PINK1/Parkin‐mediated mitophagy. Gallium–selenium nanoparticles (GaSex) scavenge reactive oxygen species, redirect neutrophils from NETosis toward bactericidal phagocytosis, eliminate methicillin‐
Kai Ye   +11 more
wiley   +1 more source

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

open access: yesAdvanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang   +8 more
wiley   +1 more source

A Coaxial Bioprinted Hydrogel With Semipermeable Sheath and Pro‐Chondrogenic Core for Articular Cartilage Repair

open access: yesAdvanced Materials, EarlyView.
A sheath‐core biomimetic hydrogel is engineered with a compartmentalized yet integrated architecture for synergistic multifunctionality. Its stiff, semipermeable sheath mimics the ECM's load‐bearing and protective roles, encapsulating a soft core that provides a pro‐chondrogenic microenvironment similar to the PCM.
Zheyuan Shi   +9 more
wiley   +1 more source

In Vivo <sup>31</sup>P-MRS of the Human Orthotopic Kidney at 3 Tesla. [PDF]

open access: yesNMR Biomed
Carlsson E   +5 more
europepmc   +1 more source

An Engineered Thio‐Amino Polymer Achieves Potent, Safe, and Broad Cell Type Delivery in the Lung Mapped by Spatial Transcriptomics

open access: yesAdvanced Materials, EarlyView.
Synthesis and screening of a polymer library produced a versatile and inhalable mRNA vehicle for the lungs (P81). Compared to a published LNP, P81 provides increased delivery efficacy, achieving widespread expression in broad cell types, with no toxicity.
Pramodkumar EK   +36 more
wiley   +1 more source

Association Between Urine pH and Kidney Outcomes in Patients with Biopsy-Proven Kidney Disease. [PDF]

open access: yesDiagnostics (Basel)
Tsuji K   +6 more
europepmc   +1 more source

Bilayered PEDOT:PSS–Collagen Scaffolds as Functional Architectures for Tissue Engineering

open access: yesAdvanced Materials Interfaces, EarlyView.
A bilayered scaffold integrates collagen and PEDOT:PSS as distinct yet interconnected 3D matrices, preserving their fibrillar and conductive characteristics. Spatial compartmentalization enables independent tailoring of each domain while maintaining mechanical stability and compatibility with electrochemical monitoring, providing a multifunctional ...
Rasha Nasser   +6 more
wiley   +1 more source

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