Results 241 to 250 of about 3,288,469 (360)

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

From heart to kidney: FGF23, SuPAR, and NAG as early biomarkers of cardiorenal syndrome in acute heart failure. [PDF]

BMC Cardiovasc Disord
El-Desouki IM, Salah NA, Aziz HMMA, El-Khawaga OY.   +3 more
europepmc   +1 more source

Peer Review #1 of "Effects of particle size on physicochemical and functional properties of superfine black kidney bean (Phaseolus vulgaris L.) powder (v0.3)"

, 2019
Xianbao Sun, Yuwei Zhang, Jing Li, Nayab Aslam, Hanju Sun, Jinlong Zhao, Zeyu Wu, Shudong He, J Ahmed, A Taher, M Mulla, A Al-Hazza, Luciano, W Beenken, E Gock, K Kurrer, C Beninger, G Hosfield, L Brewer, J Kubola, S Siriamornpun, T Herald, Y Shi, Crs Camara, C Urrea, V Schlegel, A Cardador-Martnez, G Loarca-Pia, B Oomah, H Chen, Z Wang, Z Qu, L Fu, P Dong, X Zhang, H Chen, M Zhang, B Xie, Q Chen, M Fu, F Yue, Y Cheng, Y Chen, B Zhang, Y Sun, J Zhang, H Sun, Wei Zj, S Choi, H Seo, K Lee, S Lee, Lee, E Gock, K Kurrer, E Godokov, P Bal, E Gock, W Choi, Kim Bs, D Grecka, J Korczak, Flaczyk Ejpjof, N Sciences, S He, J Li, Q He, H Jian, Y Zhang, J Wang, Sun Hj, A Heywood, D Myers, T Bailey, L Johnson, J Hu, Y Chen, D Ni, T Kahlon, F Chow, P Kethireddipalli, Y Hung, R Phillips, K Mcwatters, I Lee, Y Hung, C Chou, Y Lee, W Yoon, Y Lee, W Yoon, L Liu, J Guo, R Zhang, Z Wei, Y Deng, J Guo, M Zhang, Y Liu, F Hsieh   +99 more
openalex   +2 more sources

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Older Kidney Transplant Patients Are Over Immunosuppressed Using Standard Protocols With Differential Sex-Based Complications

Journal of Transplantation
Inji Alshaer, Rachel K. Y. Hung, Sumoyee Basu, Gabrielle Goldet, Gareth Jones, Mark Harber, Raymond Fernando, Ciara N. Magee, Reza Motallebzadeh, Ben Caplin, Alan D. Salama   +10 more
doaj   +1 more source

Leveraging extracellular vesicle biology for novel tests and therapeutics for kidney fibrosis. [PDF]

Clin Transl Med
Chiang CS, Kassianos AJ, Healy HG, Ng MSY.   +3 more
europepmc   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

The effects of elevated phosphate on the kidney - damaging the gatekeeper. [PDF]

Pflugers Arch
Mitchell T, Verma V, Fajol A, Faul C.
europepmc   +1 more source

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source