Results 21 to 30 of about 2,352,989 (309)
Kidney: polycystic kidney disease [PDF]
WIREs Developmental Biology, 2014 Polycystic kidney disease (PKD) is a life‐threatening genetic disorder characterized by the presence of fluid‐filled cysts primarily in the kidneys. PKD can be inherited as autosomal recessive (ARPKD) or autosomal dominant (ADPKD) traits. Mutations in either the PKD1 or PKD2 genes, which encode polycystin 1 and polycystin 2, are the underlying cause of
Binu M, Paul, Gregory B, Vanden Heuvel
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Chemokine receptor CCR1: A new target for progressive kidney disease [PDF]
, 2005 Infiltrating leukocytes are thought to contribute to the progression of kidney disease. Locally produced chemokines guide circulating leukocytes into the kidney, which renders therapeutic blockade of respective chemokine receptors on the leukocyte ...
Hans-Joachim Anders +3 more
core +1 more source
A new outlook towards kidney injuries [PDF]
, 2012 Acute and chronic progression of injury to the kidney leads to the failure of the renal system and has become an increasingly important cause of morbidity and mortality.
Mahesh Satwekar, Abhijeet Satwekar
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A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8 [PDF]
, 2012 Background Nephronophthisis (NPHP) as a cause of cystic kidney disease is the most common genetic cause of progressive renal failure in children and young adults.
Morahan, G. +23 more
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Renal Failure, 2018 Background: Patients with chronic kidney disease (CKD) often have CD4+ regulatory T cells (Tregs) dysfunction and chronic inflammation. We aim to investigate the effect, function, and related mechanism of low-dose IL-2 on CD4+ regulatory T cells ...
Yuanyuan Li +10 more
doaj +1 more source
Renal Failure, 2020 Background Elevated serum levels of sIL-2R are commonly observed in patients undergoing maintenance hemodialysis (MHD). However, the clinical implications in these subjects are unclear.
Xiaohong Chen +8 more
doaj +1 more source
Prescription characteristics of phosphate binders in a high pill burden for hemodialysis patients
Renal Replacement Therapy, 2021 Background Dialysis patients have to take many oral drugs, causing a high pill burden. Phosphate binders (PBs) account for a large proportion of daily pill burden; however, the relationship between patient background and prescription status of PBs is not
Nobuo Nagano +8 more
doaj +1 more source
A Rare Case Report of Giant Urinary Bladder Stone Causing Recurrent Dysuria in a Woman
Case Reports in Urology, 2022 Background. Large urinary bladder stones are not common and even less common in females. We report a case of large bladder stone presented with acute retention of urine in a female patient. Case Report.
Rojan Adhikari +6 more
doaj +1 more source
Kidney xenotransplantation [PDF]
Kidney International, 2014 Xenotransplantation using pigs as donors offers the possibility of eliminating the chronic shortage of donor kidneys, but there are several obstacles to be overcome before this goal can be achieved. Preclinical studies have shown that, while porcine renal xenografts are broadly compatible physiologically, they provoke a complex rejection process ...
Cowan, PJ, Cooper, DKC, d'Apice, AJF
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The Swiss Kidney Stone Cohort: An Observational Study to Unravel the Cause of Renal Stone Formation.
, 2017 Its nationwide character, standardized and extensive patient work-up, long-term follow-up, and significant number of patients recruited make the Swiss Kidney Stone Cohort a valuable tool to better understand the pathophysiology of kidney stone ...
Olivier Bonny +7 more
core +1 more source