Results 191 to 200 of about 19,952 (260)

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

Advanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin, Yulong Hong, Chengliang Yin, Wanyang Guo, Yaxuan Wang, Ruijiang Zeng, Ruilin Liu, Zexian Ding, Xinlin Liu, Shangqing Ren, Qiyang Liang, Yaohui Wang, Xu Zhang, João Conde, Yuan Li, Xin Ma, Liangyou Gu   +16 more
wiley   +1 more source

Analysis of preoperative risk factors for clinical decision-making in female upper urinary tract stones: a retrospective cohort study. [PDF]

BMC Urol
Mo Z, Xu B, Chen Y, Liang P, Fu Y, Gao X, Ruan Y.   +6 more
europepmc   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

When a Forgotten Kidney Stone Breaks Free: An Unexpected Case of Spontaneous Nephrocutaneous Fistula. [PDF]

Cureus
Shukr UI, Badar F, Hussain A, Khalid MU.
europepmc   +1 more source

A Humanized Anti‐gD Broadly Neutralizing Antibody Confers Complete Post‐Exposure Protection against Pseudorabies Virus

Advanced Science, EarlyView.
Pseudorabies virus (PRV), an emerging zoonotic α‐herpesvirus, causes life‐threatening human encephalitis. We identified a broad‐spectrum neutralizing antibody 6F7 targeting PRV gD. It blocks gD‐Nectin‐1 binding and membrane fusion, inhibiting replication across all PRV variants, representing a promising candidate for anti‐PRV therapy.
Yue Sun, Jianbo Liu, Shi‐Jia Xu, Meng‐Xin Wang, Hongliang Zhang, Yanhe Zhang, Zhi‐Jun Tian, Jin‐Mei Peng, Xin Yin, Tong‐Qing An, Xue‐Hui Cai, Yan‐Dong Tang   +11 more
wiley   +1 more source

Rare case of triple kidney with horseshoe fusion. [PDF]

Radiol Case Rep
El Aouadi S, Dghoughi B, Bahha S, Taibi O, Messaoud O, Aoufir OE, Jroundi L, Houssaini ZI.   +7 more
europepmc   +1 more source

Associations of metabolic syndrome and its components with complex renal calculi and stone composition: a cross-sectional study. [PDF]

Eur J Med Res
Bu S, Zhang T, Xu H, Huang X, He P, Gao J, Liu R.   +6 more
europepmc   +1 more source

[Thiazides and kidney calculi].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979
openaire   +1 more source

Impact of diabetes mellitus on stone access and surgical outcomes in patients undergoing ureteroscopic lithotripsy: a retrospective cohort study. [PDF]

BMC Urol
Küçük E, Güler H, Ordulu R, Aydın M, Öztürk U, Kırdağ MK, Ünaldı I, Atilla MK.   +7 more
europepmc   +1 more source

Acute Obstructive Uropathy Complicated by Spontaneous Fornix Rupture and Hemorrhagic Urinoma. [PDF]

Cureus
Zaid M, Al Mohdi OA, Alhayek R, Alsadi AM, Yusuf FA, Saeedi Y.   +5 more
europepmc   +1 more source