Results 221 to 230 of about 27,202 (348)

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

Advanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah, Remant KC, Amarnath Praphakar Rajendran, Saba Abbasi Dezfouli, Cezary Kucharski, Xiaoyan Jiang, Spencer B. Gibson, Joseph Brandwein, Olaf Heidenreich, Hasan Uludağ   +9 more
wiley   +1 more source

Intelligent pressure-controlled retrograde intrarenal surgery versus microchannel percutaneous nephrolithotomy to treat 2-3 cm renal calculi. [PDF]

Urolithiasis
Yang Z, Zhai Q, Wu J, Song L, Huang Y, Sun T.   +5 more
europepmc   +1 more source

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Antitumoral Efficacy of AuNRs‐Laden ECFCs In Vitro and In Vivo: Decoding the Heat and Rays Combo Treatment in Breast Cancer and Melanoma Cells

Advanced Healthcare Materials, EarlyView.
Endothelial Colony Forming Cells (ECFCs) acted as cellular cyborgs, stealthily transporting gold nanorods (AuNRs) into tumors to enable targeted near‐infrared (NIR) hyperthermia combined with radiotherapy. This approach triggers ferroptosis in melanoma and inhibits autophagy in breast cancer, revealing a tumor‐specific response to nanomaterial‐assisted
Cecilia Anceschi, Francesca Scavone, Paolo Armanetti, Luca Menichetti, Claudia Catarinicchia, Claudia Borri, Fulvio Ratto, Filippo Micheletti, Noemi Formica, Jessica Ruzzolini, Elena Frediani, Anastasia Chillà, Francesca Margheri, Mirko Severi, Rita Traversi, Patrizia Nardini, Daniele Guasti, Mario Del Rosso, Tommaso Del Rosso, Lisa Giovanelli, Cinzia Talamonti, Monica Mangoni, Isacco Desideri, Silvia Burchielli, Fabiola Pajar, Gabriella Fibbi, Anna Laurenzana   +26 more
wiley   +1 more source

RISK FACTORS FOR RENAL CALCULI IN PATIENTS WITH CROHN'S DISEASE. [PDF]

Arq Gastroenterol
Cury DB, Cury LCB, Michelletti AC, Oliveira RA, Gonçalves EAP, Schor N.   +5 more
europepmc   +1 more source

3D Bioprinted Renal Constructs Using Kidney‐Specific ECM Bioink System on Kidney Regeneration

Advanced Healthcare Materials, EarlyView.
A kidney‐specific bioink derived from decellularized porcine kidney tissue supports the encapsulation, viability, and maturation of human primary kidney cells within 3D bioprinted constructs. In vivo, it also promotes the recruitment of host renal progenitor cells, collectively enhancing structural and functional regeneration of renal tissue.
Gabriel Carreno‐Galeano, Mohamed Ali, James J. Yoo, Sang Jin Lee, Anthony Atala   +4 more
wiley   +1 more source

Clinical advantages of suctioning flexible ureteroscopy with intelligent pressure control on treating large upper urinary tract calculi. [PDF]

Front Surg
Cai W, Zheng B, Li X, Gao X, Zhang Z, Lu Y, Zhao H, You J, Zheng G, Bao W, Lai Y, Lv Y.   +11 more
europepmc   +1 more source

Squamous cell carcinoma of the kidney in a patient with staghorn calculi

, 2019
Soumya Mondal, Ankit Kumar, Souvik Chatterjee, Krishnendu Maity, Dilip Kumar Pal   +4 more
openalex   +2 more sources

Extra corporeal shock wave lithotripsy of calculi located in lower calyx of left kidney in a spinal cord injury patient who has implantation of baclofen pump in the ipsilateral loin [PDF]

, 2002
S Vaidyanathan, H. W. Johnson, Gurpreet Singh, BM Soni, KF Parsons   +4 more
openalex   +1 more source

Recurrent renal calculi in coexistence of horseshoe kidney and medullary sponge kidney

Urology Annals, 2017
Aditya S. Pawar, Wisit Cheungpasitporn, Stephen B. Erickson   +2 more
openaire   +4 more sources