Results 231 to 240 of about 20,118 (262)

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

open access: yesAdvanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang   +22 more
wiley   +1 more source

Emphysematous pyelonephritis and infection-related calculi. [PDF]

open access: yesPediatr Nephrol
Tzvi-Behr S   +5 more
europepmc   +1 more source

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider   +20 more
wiley   +1 more source

Rare Case of <i>Aspergillus fumigatus</i> Isolated from Renal Stone in an Immunocompetent Patient. [PDF]

open access: yesInt Med Case Rep J
Bhujel R   +9 more
europepmc   +1 more source

S.T.O.N.E. nephrolithometry for kidney calculi

open access: yesIndian Journal of Urology, 2013
Kuldeep Sharma
doaj  

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