Results 111 to 120 of about 1,031,295 (331)

Bubbly cavitating flow generation and investigation of its erosional nature for biomedical applications [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Akbas, A, Gozuacik, D, Kosar, A, Kubilay, A, Oral, O, Sahin, O   +6 more
core  

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Kidney Cancer [PDF]

Journal of the National Comprehensive Cancer Network, 2009
Mario Vaccaro, Claudio Guarneri, Richard F. Ambinder, S. Diane Hayward, Marcia Spinelli Casanova, Oladapo Adewuya, Ferid Murad, Zoran Gatalica, Alexander K. C. Leung, William Lane M. Robson, Khalid Hussain, Dieter Metze, Stefan R. Bornstein, Alexander K. C. Leung, Kunihiko Suzuki, Kenneth C. Bilchick   +15 more
openaire   +2 more sources

Histopathology based AI model predicts anti-angiogenic therapy response in renal cancer clinical trial

Nature Communications
Anti-angiogenic (AA) therapy is a cornerstone of metastatic clear cell renal cell carcinoma (ccRCC) treatment, but not everyone responds, and predictive biomarkers are lacking.
Jay Jasti, Hua Zhong, Vandana Panwar, Vipul Jarmale, Jeffrey Miyata, Deyssy Carrillo, Alana Christie, Dinesh Rakheja, Zora Modrusan, Edward Ernest Kadel, Niha Beig, Mahrukh Huseni, James Brugarolas, Payal Kapur, Satwik Rajaram   +14 more
doaj   +1 more source

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

Advanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou, Jagadish Krishnappa, Justin B. Schaal, Prasad Tongaonkar, Dat Q. Tran, Wenchao Gu, Yung‐Fu Chang, Michael E. Selsted, Shaoyi Jiang, Samir Mitragotri, Michael Super, Christopher J. Bettinger   +11 more
wiley   +1 more source

Extracranial Palliative Radiation Therapy for Renal Cell Carcinoma

Advances in Radiation Oncology
Purpose: Symptom management is an integral component of care for patients with renal cell carcinoma (RCC). We evaluated the efficacy of radiation therapy (RT) and factors influencing symptom in an ethnically diverse patient population.
Young Suk Kwon, MD, MPH, Eric Hsu, MD, PhD, Maggie Stein, BSPH, Alana Christie, MS, Aurelie Garant, MD, Neil B. Desai, MD, Andrew Wang, MD, Daniel X. Yang, MD, Allen Yen, MD, Mihailo Miljanic, MD, Kevin D. Courtney, MD, PhD, Hans Hammers, MD, PhD, Tian Zhang, MD, Waddah Arafat, MD, Qian Qin, MD, Suzanne Cole, MD, James Brugarolas, MD, PhD, Robert Timmerman, MD, Raquibul Hannan, MD, PhD   +18 more
doaj   +1 more source

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

Advanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li, E Pang, Snehasish Debnath, Jia Hong, Aojun Qiu, Dongeun Kim, Goeun Kim, Minhuan Lan, Min‐Goo Lee, Qian‐Yong Cao, Jong Seung Kim   +10 more
wiley   +1 more source

RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer [PDF]

, 2017
Jae Ho Lee, Yong Geun Jeon, Kyoung Hwa Lee, Hye Won Lee, Jeu Park, Hagoon Jang, Minyong Kang, Hye Sun Lee, Hee Jin Cho, Do‐Hyun Nam, Cheol Kwak, Jae Bum Kim   +11 more
openalex   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Cancer Screening in Solid Organ Transplant Recipients: A Focus on Screening Liver, Lung, and Kidney Recipients for Cancers Related to the Transplanted Organ

, 2021
Atit Dharia, Jacinthe Boulet, Vikas S. Sridhar, Abhijat Kitchlu   +3 more
openalex   +1 more source