Results 231 to 240 of about 1,031,295 (331)

Occupational exposures and kidney cancer among 25 000 male offshore petroleum industry workers: relative risks and healthy worker survivor bias. [PDF]

Am J Epidemiol
Shala NK, Veierød MB, Babigumira R, Berge LAM, Samuelsen SO, Kirkeleit J, Bråtveit M, Friesen MC, Keil AP, Silverman DT, Rothman N, Qing L, Stenehjem JS, Grimsrud TK.   +13 more
europepmc   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Racial differences in kidney cancer histology and outcome: A nationwide study from the UroCCR Cohort. [PDF]

Cancer
Lu X, Bernhard JC, Margue G, Audenet F, Doumerc N, Merlin P, Roupret M, Waeckel T, Champy C, Surlemont L, Olivier J, Branger N, Parier B, Gaillard V, Bruyere F, Fontenil A, Michel C, Vignot L, Descotes JL, Loison G, Guillotreau J, Taha F, Panthier F, De Vergie S, Ouzaid I, Boissier R, Patard JJ, Gimel P, Duquesne I, Chalhoub K, Bigot P, Malouf GG.   +31 more
europepmc   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Hematuria and Kidney Failure in a Patient with Kidney Cancer. [PDF]

Kidney360
Fujita Y, Watanabe S, Ichikawa D.
europepmc   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Management and optimization of chronic renal insufficiency in the setting of kidney cancer A Systematic Review. [PDF]

Int Braz J Urol
Cobb JK, Miyagi H, Chahoud J, Bassil C, Spiess PE.   +4 more
europepmc   +1 more source

PreKiCan: A PARAM Utkarsh-Powered Model for Early Kidney Cancer Identification

Shubham Ranswal
openalex   +2 more sources

Expression Profiling Predicts Survival in Kidney Cancer

, 2005

openalex   +2 more sources

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source