Results 321 to 330 of about 921,567 (386)

A decade long insight into patient views on kidney cancer care delivery. [PDF]

BJU Int
Rossi SH, Fox G, Packer M, Greaves A, Tran M, Charnley N, Oades G, Boleti E, Stewart GD.   +8 more
europepmc   +1 more source

PRMT5 Inhibitor Synergizes with Chemotherapy to Induce Resembling Mismatch Repair Deficiency and Enhance Anti‐TIGIT Therapy in Microsatellite‐Stable Colorectal Cancer

Advanced Science, EarlyView.
Microsatellite‐stable (MSS) colorectal cancer (CRC) resists immunotherapy. PRMT5 inhibition enhances CPT‐11 sensitivity, inducing a PMS2‐deficient‐like state and cytosolic dsDNA release, which activates the cGAS‐STING pathway to promote anti‐tumor immunity. However, this combination therapy upregulates TIGIT expression on CD8+ T cells, and the addition
Jiang Zhu, Shenao Fu, Xi Zou, Hanjiang Zeng, Guangzu Cui, Yinghui Peng, Diya Tang, Fan Zhang, Hong Shen, Shan Zeng, Ying Han   +10 more
wiley   +1 more source

Trends in Stage-Specific Kidney Cancer Incidence in Kazakhstan, 2005-2019. [PDF]

Asian Pac J Cancer Prev
Igissin N, Dyakov S, Telmanova Z, Kudaibergenova I, Ayaganov S, Turebayev D, Jexenova A, Igissinova GS, Maukayeva S, Lust V, Grigorevsky V, Shelestyuk A, Syzdykov N, Shishkin I, Bilyalova Z.   +14 more
europepmc   +1 more source

Engineered Genetic Circuits Activated by Bezafibrate Improve ESC‐Based TAA Cancer Vaccine Efficacy and PD‐L1 Nanobody Therapy

Advanced Science, EarlyView.
Synthetic gene circuits regulated by bezafibrate are developed to express tumor antigens and PD‐L1 nanobody (PD‐L1nb), enhancing cancer immunotherapy. Delivered via HEK293T cells, ESCs, or directly injected the plasmids containing the circuit into the tumor, the circuits reduce tumor growth, boost CD8+ T cells, and minimize T cell exhaustion.
Meiling Jin, Shuzhen Liu, Mingshuo Zhan, Jian‐Dong Huang   +3 more
wiley   +1 more source

A Novel Nomogram for the Prediction and Evaluation of Prognosis in Patients with Early-onset Kidney Cancer: a Population-based Study. [PDF]

J Cancer
Lv D, Wang Q, Sun K, Li J, Zhou H, Wen J, Shuang W.   +6 more
europepmc   +1 more source

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin, Ye Wu, Xiao‐Hui Liang, Min Tang, Xin Sun, Sheng‐Xin Lu, Jin‐Mei Jin, Xin Guo, Bei Wang, Hong‐Zhuan Chen, Wei‐Dong Zhang, Xin Luan   +11 more
wiley   +1 more source

Research progress on the correlation between obesity and the occurrence and development of kidney cancer: a narrative review. [PDF]

Transl Cancer Res
Kang L, Chen X, Qi P, Ma Z, Han D, Zhang X, Shang P.   +6 more
europepmc   +1 more source

Identification and validation of molecular subtypes and prognostic models in patients with kidney cancer based on differential genes based on B cells: a multiomics analysis. [PDF]

BMC Cancer
Sun J, Song S, Ma Q, Chen F, Chen X, Wu G.   +5 more
europepmc   +1 more source

Postdiagnostic use of antihypertensive medications and survival in colorectal, lung, corpus uteri, melanoma and kidney cancer patients with hypertension. [PDF]

BMC Cancer
Everatt R, Kuzmickienė I, Brasiūnienė B, Vincerževskienė I, Intaitė B, Cicėnas S, Lisauskienė I.   +6 more
europepmc   +1 more source