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Cancer in Kidney Transplantation
Urologia Internationalis, 2008Cancer in the transplanted kidney is rare, and its clinical and surgical management can be controversial. We report 3 cases of cancer in renal transplantation (1 case of renal cell carcinoma and 2 cases of transitional cell carcinoma) and their treatment.
Zani D. +5 more
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The Cancer Journal, 2016
The number of new cases of renal cell carcinoma has been steadily increasing since the 1960s, reaching 62,000 and 89,000 annually in the United States and Europe, respectively, in 2016. The current standard of care for early-stage disease is nephron-sparing surgery, which has a demonstrated long-term disease-free survival and an acceptable safety ...
S Brandon, Hancock +1 more
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The number of new cases of renal cell carcinoma has been steadily increasing since the 1960s, reaching 62,000 and 89,000 annually in the United States and Europe, respectively, in 2016. The current standard of care for early-stage disease is nephron-sparing surgery, which has a demonstrated long-term disease-free survival and an acceptable safety ...
S Brandon, Hancock +1 more
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European Urology Supplements, 2006
Abstract Objective This paper reviews present evidence concerning kidney cancer epidemiology. Methods The review was based on the most recent and relevant papers reported in the literature. Results Kidney cancer is one of the most important urologic cancers because of high lethality and increasing incidence in most countries.
RUBAGOTTI, ALESSANDRA +2 more
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Abstract Objective This paper reviews present evidence concerning kidney cancer epidemiology. Methods The review was based on the most recent and relevant papers reported in the literature. Results Kidney cancer is one of the most important urologic cancers because of high lethality and increasing incidence in most countries.
RUBAGOTTI, ALESSANDRA +2 more
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Clinical Obstetrics and Gynecology, 2002
Kidney cancers are relatively rare and account for only 3% of adult malignancies. Although these tumors are more common in men than in women, with a male:female ratio of 1.5:1, the kidney is a significant source of cancer diagnoses and death in women. In the United States in 2002, it is estimated that 12,700 women will be diagnosed with kidney cancer ...
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Kidney cancers are relatively rare and account for only 3% of adult malignancies. Although these tumors are more common in men than in women, with a male:female ratio of 1.5:1, the kidney is a significant source of cancer diagnoses and death in women. In the United States in 2002, it is estimated that 12,700 women will be diagnosed with kidney cancer ...
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, 1989 Kidney tumours may originate in the renal parenchyma or in the urothelium of the cavity system (carcinoma of the renal pelvis). The two types of tumour present essential differences with regard to incidence, the preoperative diagnostic procedures needed, treatment and prognosis (Vahlensieck and van der Weyer 1960).
N. Jaeger, W. Vahlensieck
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Radiologic Clinics of North America, 2007
Advances in molecular genetics have expanded the understanding of renal cell tumors. Now it is understood that renal cortical tumors are a family of neoplasms with distinct cytogenetics and molecular defects, unique histopathologic features, and different malignant potentials.
Ariadne M. Bach +2 more
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Advances in molecular genetics have expanded the understanding of renal cell tumors. Now it is understood that renal cortical tumors are a family of neoplasms with distinct cytogenetics and molecular defects, unique histopathologic features, and different malignant potentials.
Ariadne M. Bach +2 more
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Urologic Oncology: Seminars and Original Investigations, 2009
Kidney cancer in the elderly patient is a real challenge for the oncologic urologist. With the aging population, we will face more patients with renal cell carcinoma in senior adults. There is evidence that elderly patients with RCC have more aggressive disease and lower cancer-specific survival.
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Kidney cancer in the elderly patient is a real challenge for the oncologic urologist. With the aging population, we will face more patients with renal cell carcinoma in senior adults. There is evidence that elderly patients with RCC have more aggressive disease and lower cancer-specific survival.
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Urologic Clinics of North America, 2003
Significant advances have been made in the understanding of the genetic basis of familial renal neoplasia. Identification of key genes in the pathogenesis of various hereditary renal cancer syndromes has provided opportunities to screen family members at risk and to explore the significance of these genetic abnormalities in the development and genesis ...
W. Marston Linehan +3 more
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Significant advances have been made in the understanding of the genetic basis of familial renal neoplasia. Identification of key genes in the pathogenesis of various hereditary renal cancer syndromes has provided opportunities to screen family members at risk and to explore the significance of these genetic abnormalities in the development and genesis ...
W. Marston Linehan +3 more
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Immunotherapy of Kidney Cancer
Current Clinical Pharmacology, 2011Renal cell carcinoma (RCC) accounts for 4% of all new cancer cases in males and 3% in females in the US. Compared to other solid tumors, it does not respond to traditional management modalities, such as chemotherapy and radiation therapy. However, it appears to be an immune-responsive tumor and several immunotherapeutic strategies have been ...
Petros Grivas, Bruce G. Redman
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The Immunobiology of Kidney Cancer
Journal of Clinical Oncology, 2018Although kidney cancer (renal cell carcinoma [RCC]) is susceptible to immunotherapy, the immunologic aspects of the tumor microenvironment (TME) in RCC are relatively unique among tumor types. In RCC, baseline CD8 T-cell infiltration is associated with a worse prognosis. In addition, kidney cancer responds to programmed death-1/programmed death-ligand
Mark N. Stein, Charles G. Drake
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