Results 91 to 100 of about 587,070 (347)

Role of contrast-enhanced ultrasound (CEUS) in paediatric practice: an EFSUMB position statement [PDF]

, 2016
The use of contrast-enhanced ultrasound (CEUS) in adults is well established in many different areas, with a number of current applications deemed off-label, but the use supported by clinical experience and evidence.
Cantisani, Vito, Deganello, A., Dietrich, C. F., Duran, C., Franke, D., Gilja, O. H., Harkanyi, Z., Kosiak, W., Miele, Vittorio, Ntoulia, A., Piskunowicz, M., Sellars, M. E., Sidhu, P. S   +12 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

SOX9-dependent fibrosis drives renal function in nephronophthisis

EMBO Molecular Medicine
Fibrosis is a key feature of a broad spectrum of cystic kidney diseases, especially autosomal recessive kidney disorders such as nephronophthisis (NPHP).
Maulin Mukeshchandra Patel, Vasileios Gerakopoulos, Bryan Lettenmaier, Eleni Petsouki, Kurt A Zimmerman, John A Sayer, Leonidas Tsiokas   +6 more
doaj   +1 more source

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

, 2015
Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R., Alvarado, A., Lakshmanaperumal, N., McClain, M., McKinney, S., Rink, J., Vu, H.   +6 more
core   +1 more source

World's longest surviving liver-pancreas recipient [PDF]

, 2007
In July 1988, the liver and pancreas of a cadaveric donor were transplanted separately into a man with type 1 diabetes with end-stage chronic hepatitis B virus.
Alessiani, Calne, Cecka, Farrell, Groth, Lillehei, Petruzzo, Philosophe, Pirenne, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stratta, Sutherland, Thai, Young   +20 more
core   +1 more source

Programmatic regulation of macrophage polarization by HAp@MXene nanocomposites to promote bone repair

BMEMat, EarlyView.
HAp@MXene nanocomposites could achieve the programmed regulation of macrophage polarization. They first induce M1 polarization through magnetoelectric induction to combat infection. Subsequently, controlled Ca2+ release drives M2 polarization to promote tissue regeneration. This dual mechanism accelerates bone defect repair and highlights the potential
Laisen Cui, Haina Huang, Yubo Zheng, Jiahao Zhang, Han Hai, Kai Bian, Zhichao Feng, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Shan Lu, Bojun Xie, Ke Gao, Benjie Wei, Ya Liu, Chunhui Sun, Hong Liu, Chao Liu   +16 more
wiley   +1 more source

Rare Combination of Phenotypes of Karyomegalic Interstitial Nephritis and Autosomal Recessive Polycystic Kidney Disease in an Omani Child

Oman Medical Journal
Autosomal recessive polycystic kidney disease is one of the most prevalent inherited cystic kidney diseases in infants and children, common in highly consanguineous societies such as Oman. Karyomegalic interstitial nephritis is a rare cause of hereditary
Intisar Al Alawi, Maryam Al Shehhi, Naifain Al Kalbani, Aliya Al Hosni, Ashwaq Al Mimani, Issa Al Salmi, John A. Sayer   +6 more
doaj   +1 more source

miR-25-3p promotes proliferation and inhibits autophagy of renal cells in polycystic kidney mice by regulating ATG14-Beclin 1

Renal Failure, 2020
MicroRNAs are involved in the regulation of the autophagy and proliferation in several diseases. This study aims to verify the role of miR-25-3p in the proliferation and autophagy of renal cells in polycystic kidney disease (PKD). We found that kidney to
Guojian Liu, Xiaowen Kang, Ping Guo, Yu Shang, Ruomei Du, Xiyue Wang, Liting Chen, Rui Yue, Fanwu Kong   +8 more
doaj   +1 more source

Marine silicon for biomedical sustainability

BMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han, Zhibo Yang, Wei Xia, Chengtie Wu   +3 more
wiley   +1 more source

Current Status of Defensins and Their Role in Innate and Adaptive Immunity [PDF]

, 2002
Naturally occurring antimicrobial cationic polypeptides play a major role in innate and adaptive immunity. These polypeptides are found to be either linear and unstructured or structured through disulfide bonds.
Dentino, Andrew R., Raj, Periathamby A.
core   +1 more source