Results 161 to 170 of about 617,774 (332)

Approach to inherited cystic kidney disease

, 2015
Kistik böbrek hastalıkları, kalıtımsal böbrek hastalıkları içinde en sık görülen grup olup, her biri farklı etiyoloji, patogenez, klinik prezentasyon ve prognoza sahiptir.
Çakar, Nilgün, Taktak, Aysel
core  

A Novel Renal Manifestation in <i>GLIS3</i>-Related Disorder in a Pediatric Patient With Cystic Nephroma. [PDF]

J Med Cases
Alharbi I, Alharbi DK, Abdelrahim R, Alzahrani BF.   +3 more
europepmc   +1 more source

Kidney Cancer and Diabetes Mellitus: A Population-Based Case-Control Study in Taiwan

, 2014
Introduction: The purpose of this study was to explore whether diabetes mellitus (DM) correlates with the risk of kidney cancer in Taiwan. Materials and Methods: We designed a population-based case-control study from the Taiwan National Health Insurance ...
Lai, Shih Wei;Liao, Kuan Fu;Lai, Hsueh Chou;Tsai, Pang Yao;Sung, Fung Chang;Chen, Pei Chun, 陳培君   +1 more
core  

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Spatiotemporal dynamics of renal distal convoluted tubule dilatation and cyst formation in nephronophthisis type 1 mice. [PDF]

Ren Fail
Zhang W, Xu G, Su X, Lai J, Xue Z, Li T, Huang H, Li R, Sun L, Li Y.   +9 more
europepmc   +1 more source

Tubuloids derived from human adult kidney and urine for personalized disease modeling

Nature Biotechnology, 2019
Frans Schutgens, M. Rookmaaker, T. Margaritis, Anne C. Rios, C. Ammerlaan, J. Jansen, Linda Gijzen, M. Vormann, A. Vonk, M. Viveen, Fjodor A Yousef Yengej, Sepideh Derakhshan, K. M. de Winter-de Groot, B. Artegiani, R. van Boxtel, E. Cuppen, A. Hendrickx, M. M. van den Heuvel-Eibrink, E. Heitzer, H. Lanz, J. Beekman, J. Murk, R. Masereeuw, F. Holstege, J. Drost, M. Verhaar, H. Clevers   +26 more
semanticscholar   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Prenatal Diagnosis of Renal Cysts and Diabetes Syndrome (RCAD): A Case Report. [PDF]

Am J Case Rep
Manasar-Dyrbuś M, Stojko R, Paul-Samojedny M, Winkowska E, Staniczek J.   +4 more
europepmc   +1 more source

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen, Nils Johan Fredriksson, Michael Andresen, Jon Jonasson, Malin Lindqvist Appell, Henrik Gréen   +5 more
wiley   +1 more source

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Dysfunction in Human Diseases: Molecular Mechanisms and Pathophysiological Implications. [PDF]

Cells
Rahman MS, Daira M.
europepmc   +1 more source