Results 221 to 230 of about 542,680 (355)

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

The FEBS Journal, EarlyView.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain, Gonzalo S. Tejeda, George S. Baillie   +2 more
wiley   +1 more source

Extrarenal Clinical Features are Reported for Most Genes Implicated in Genetic Kidney Disease. [PDF]

Kidney Int Rep
Serrano B, Savige J.
europepmc   +1 more source

Mitochondrial dysfunction in inherited renal disease and acute kidney injury

Nature Reviews Nephrology, 2016
F. Emma, G. Montini, S. Parikh, L. Salviati   +3 more
semanticscholar   +1 more source

Renal cell carcinoma with fibromyomatous stroma (RCC FMS) and with hemangioblastoma‐like areas is part of the RCC FMS spectrum in patients with tuberous sclerosis complex

Histopathology, EarlyView.
We report on three patients with Tuberous Sclerosis Complex (TSC) who had renal cell carcinomas with fibromyomatous stroma (RCC FMS), demonstrating a coexistent haemangioblastoma (HB)‐like morphology. Our findings support the conclusion that HB‐like features are part of the spectrum of RCC FMS with TSC/MTOR alterations.
Katherina Baranova, Jacob A Houpt, Deaglan Arnold, Andrew A House, Laura Lockau, Lindsay Ninivirta, Stephen Pautler, Haiying Chen, Madeleine Moussa, Rola Saleeb, Jose A Gomez, Asli Yilmaz, Farshid Siadat, Adrian Box, Douglas J Mahoney, Franz J Zemp, Manal Gabril, Kiril Trpkov   +17 more
wiley   +1 more source

Late-Onset Crizotinib-Associated Renal Cysts With Subsequent Regression Following Dose Reduction: A Case Report. [PDF]

Thorac Cancer
Yoon JY, Jeong WG, Choi YD, Kang SJ, Park HK, Oh HJ, Park CK, Oh IJ, Kim YC.   +8 more
europepmc   +1 more source

G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease

Proceedings of the National Academy of Sciences of the United States of America, 2012
Michelle P. Kwon, T. Pavlov, K. Nozu, Shauna Rasmussen, D. Ilatovskaya, A. Lerch-Gaggl, Lauren M. North, Hyunho Kim, F. Qian, W. Sweeney, E. Avner, J. Blumer, A. Staruschenko, F. Park   +13 more
semanticscholar   +1 more source

Current Evidences and Future Perspectives in the Management of Metastatic Non‐Clear Cell Renal Cell Carcinoma

International Journal of Urology, EarlyView.
ABSTRACT Renal cell carcinoma is a heterogeneous disease with diverse phenotypes. Renal cell carcinoma classification is based on morphological and molecular characteristics and falls into 2 main categories: clear cell renal cell carcinoma and non‐clear cell renal cell carcinoma.
Shotaro Nakanishi, Junichi Inokuchi
wiley   +1 more source

Impact of body mass index on outcomes of non-cystic fibrosis bronchiectasis. [PDF]

BMJ Open Respir Res
Hsu WH, Shiau BW, Wei YF, Lai CC, Chen CY.   +4 more
europepmc   +1 more source

Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases

Hepatology, 2013
T. Masyuk, Brynn N. Radtke, Angela J. Stroope, J. Banales, S. Gradilone, B. Huang, A. Masyuk, M. Hogan, V. Torres, N. LaRusso   +9 more
semanticscholar   +1 more source

Hereditary and acquired cystic disease of the kidney

Kidney International, 1994
Godela M. Fick, Patricia A. Gabow
openaire   +3 more sources