Results 241 to 250 of about 587,070 (347)
ABSTRACT Background Sarcopenia, an important complication of chronic obstructive pulmonary disease (COPD), is significantly associated with increased mortality. Systemic inflammation is an important trigger of COPD‐related skeletal muscle dysfunction. Calprotectin is a damage‐associated molecular pattern involved in the inflammatory response, but its ...
Liwei Liao +9 more
wiley +1 more source
Are Image-Based Deep Learning Algorithms of Kidney Volume in Polycystic Kidney Disease Ready for Clinical Deployment? A Systematic Review and Meta-Analysis. [PDF]
Colliander E +6 more
europepmc +1 more source
ABSTRACT Temporomandibular joint osteoarthritis (TMJ‐OA) is a progressive degenerative disorder, for which therapeutic interventions remain limited. The disruption of metabolic homeostasis plays a critical role in the pathogenesis and advancement of TMJ‐OA.
Bowen Meng +19 more
wiley +1 more source
Anticodon-edited tRNA enables translational readthrough of COL4A5 premature termination codons. [PDF]
Omachi K, Porter JJ, Lueck JD, Miner JH.
europepmc +1 more source
Explore the key challenges and limitations in nanomedicine for biofilm treatment, from drug loading efficiency to antimicrobial resistance. ABSTRACT Antimicrobial resistance continues to rise globally, with biofilm‐associated infections intensifying the clinical burden through persistent tolerance to antibiotics and evasion of immune responses ...
Husni Farah +8 more
wiley +1 more source
Genetic diagnosis and prenatal diagnosis of patients with cystic kidney disease in Southwest China. [PDF]
Zhou C, Xiao Y, Xie H, Wei X, Wang J.
europepmc +1 more source
Organ‐on‐a‐Chip Technology and Global Multi‐Omics: Current Applications and Future Directions
Comparative analysis of multiple cell culture models. The 3D microfluidic organ‐on‐a‐chip, which is superior to the existing models in multiple aspects, can be more conducive to new studies and discoveries related to human beings. Created with BioRender (www.biorender.com).
Xuxia Cao +7 more
wiley +1 more source
Synchronous angiomyolipoma with epithelial cysts and clear cell renal cell carcinoma: a case report. [PDF]
Wang J +7 more
europepmc +1 more source
Progress in RNA‐Targeted Therapeutics for Human Diseases
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang +10 more
wiley +1 more source

