Results 271 to 280 of about 542,680 (355)

Pathogenic variants prevalence patients with diabetic kidney disease in Japan: A descriptive study. [PDF]

J Diabetes Investig
Hashiba T, Sugawara Y, Hirakawa Y, Sato D, Inagi R, Nangaku M.   +5 more
europepmc   +1 more source

Limited association between HRR gene alterations and HRD in molecular tumor board cancer samples: Who should be tested for HRD?

International Journal of Cancer, Volume 157, Issue 5, Page 964-979, 1 September 2025.
What's new? Currently, no published data on homologous recombination deficiency (HRD) testing in the setting of molecular tumor boards exist. This study in a cohort of 237 patients encompassing 24 different tumor entities assessed by a molecular tumor board shows that inactivating alterations of BRCA1/2 are not always associated with an elevated ...
Christoph Schubart, Lars Tögel, Maria Giulia Carta, Philip Hetzner, Lina Helbig, Charlotte Zaglas, Maria Ziegler, Robert Stöhr, Annett Hölsken, Juliane Hoyer, Fulvia Ferrazzi, Clemens Neufert, Sebastian Lettmaier, Marianne Pavel, Henriette Golcher, Sarina K. Mueller, Florian Fuchs, Carla E. Schulmeyer, Matthias W. Beckmann, Bernd Wullich, Abbas Agaimy, Andre Reis, Arndt Hartmann, Norbert Meidenbauer, Silvia Spoerl, Florian Haller, Evgeny A. Moskalev   +26 more
wiley   +1 more source

Urothelial carcinoma mimicking Bosniak IV cystic mass: A case report. [PDF]

Radiol Case Rep
Jung J, Shu C, Hassani P, Phillipi M, Lee V, Houshyar R, Shi J.   +6 more
europepmc   +1 more source

MRI Assessment of Lung Water Density in Individuals Previously Infected With COVID‐19: A Cross‐Sectional Study

Journal of Magnetic Resonance Imaging, Volume 62, Issue 3, Page 767-778, September 2025.
ABSTRACT Background Lung damage in post‐acute COVID‐19 is a common clinical finding. Lung water density (LWD) imaging using ultrashort echo time (UTE) MRI with proton‐density weighting is sensitive to edema and fibrosis. Purpose To characterize LWD in COVID‐19 survivors, compared with a healthy cohort. Study Type Retrospective cohort.
Christopher Keen, Justin Grenier, Peter Šereš, Robert Stobbe, James White, Christian Beaulieu, Rachel Sherrington, Amy Kirkham, D. Ian Paterson, Richard Thompson   +9 more
wiley   +1 more source

Variable Phenotypic Expression of <i>PAX2</i> Variants in Two Lithuanian Families with Kidney Disease. [PDF]

Medicina (Kaunas)
Brazdziunaite D, Mazur G, Miglinas M, Utkus A.   +3 more
europepmc   +1 more source

Melioidosis in Asia‐Pacific Nations: Expanding Boundaries but Unknowns Remain

Respirology, EarlyView.
Bart J. Currie, Ella M. Meumann
wiley   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, Volume 45, Issue 5, Page 1452-1465, September 2025.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

The impact of maternal obesity on polycystic kidney disease progression in a mouse model. [PDF]

Am J Physiol Renal Physiol
Miller SJ, Hill K, Darby I, Nusrat F, Friedman JE, Rudolph MC, Zimmerman KA.   +6 more
europepmc   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava, Kalyani Eswar, Sasvat Sayee Ram Ramesh, Akshit Prajapati, Tanvi Sonpipare, Apoorva Basa, Mounika Gubige, Sribala Ponnapalli, Shashidhar Thatikonda, Aravind Kumar Rengan   +9 more
wiley   +1 more source