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Annual Review of Pathology: Mechanisms of Disease, 2007
This review focuses on the mechanisms that underlie the development of human renal cystic diseases. A pathological, clinical, and pathophysiological overview is given. Initial analysis of the cell biology of inappropriate hyperproliferation accompanied by fluid secretion of cyst-lining epithelia has been followed by the elucidation of fundamental ...
Patricia D. Wilson, Beatrice Goilav
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This review focuses on the mechanisms that underlie the development of human renal cystic diseases. A pathological, clinical, and pathophysiological overview is given. Initial analysis of the cell biology of inappropriate hyperproliferation accompanied by fluid secretion of cyst-lining epithelia has been followed by the elucidation of fundamental ...
Patricia D. Wilson, Beatrice Goilav
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Current Opinion in Nephrology and Hypertension, 1997
The goal of understanding the primary defects that lead to renal cystic diseases has proved to be an elusive one, despite 3 decades of physiologic and genetic investigation. Within the past 2 years the genes responsible for type 1 and type 2 autosomal dominant polycystic kidney disease have been identified.
Vicente E. Torres +2 more
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The goal of understanding the primary defects that lead to renal cystic diseases has proved to be an elusive one, despite 3 decades of physiologic and genetic investigation. Within the past 2 years the genes responsible for type 1 and type 2 autosomal dominant polycystic kidney disease have been identified.
Vicente E. Torres +2 more
openaire +3 more sources
Clinical Scenarios in Chronic Kidney Disease: Cystic Renal Diseases.
Contributions to Nephrology, 2016Cysts are frequently found in chronic kidney disease (CKD) and they have a different prognostic significance depending on the clinical context. Simple solitary parenchymal cysts and peripelvic cysts are very common and they have no clinical significance.
M. Meola, S. Samoni, Ilaria Petrucci
semanticscholar +1 more source
2012
Renal cysts are one of the most commonly detected abnormalities of kidneys. They can be associated with congenital or acquired disorders. Simple and complex cysts can be observed in kidneys which have different clinical management. Simple cysts do not require treatment, but complex cysts should be evaluated and followed up with appropriate imaging ...
Agnes B. Fogo, Michael Kashgarian
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Renal cysts are one of the most commonly detected abnormalities of kidneys. They can be associated with congenital or acquired disorders. Simple and complex cysts can be observed in kidneys which have different clinical management. Simple cysts do not require treatment, but complex cysts should be evaluated and followed up with appropriate imaging ...
Agnes B. Fogo, Michael Kashgarian
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JAMA pediatrics, 2018
Importance Prenatal and neonatal cystic kidney diseases are a group of rare disorders manifesting as single, multiple unilateral, or bilateral cysts or with increased echogenicity of the renal cortex without macroscopic cysts.
C. Gimpel +15 more
semanticscholar +1 more source
Importance Prenatal and neonatal cystic kidney diseases are a group of rare disorders manifesting as single, multiple unilateral, or bilateral cysts or with increased echogenicity of the renal cortex without macroscopic cysts.
C. Gimpel +15 more
semanticscholar +1 more source
American Journal of Kidney Diseases, 2021
Massively Parallel Sequencing identifies pathogenic variants in the genes affected in Alport syndrome (COL4A3 - COL4A5) in up to 30 % of individuals with focal and segmental glomerulosclerosis (FSGS), 10 % of those with kidney failure of unknown cause ...
J. Savige, P. Harraka
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Massively Parallel Sequencing identifies pathogenic variants in the genes affected in Alport syndrome (COL4A3 - COL4A5) in up to 30 % of individuals with focal and segmental glomerulosclerosis (FSGS), 10 % of those with kidney failure of unknown cause ...
J. Savige, P. Harraka
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Cystic kidney diseases: all roads lead to the cilium.
Physiology, 2004Cystic kidney disorders are one of the leading causes of end-stage renal disease. Numerous experimental animal models have been used to understand the disease pathogenesis.
Qihong Zhang +2 more
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Renal Cell Cancer and Chronic Kidney Disease.
Advances in Chronic Kidney Disease, 2021The association between chronic kidney disease (CKD) and renal cell carcinoma (RCC) is bidirectional and multifactorial. Risk factors such as hypertension, diabetes mellitus, obesity, and smoking increase the risk of both CKD and RCC. CKD can lead to RCC
D. Saly +3 more
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Cystic kidney diseases in children
Archives de Pédiatrie, 2023Cystic kidney disease comprises a broad group of heterogeneous diseases, which differ greatly in age at onset, disease manifestation, systemic involvement, disease progression, and long-term prognosis. As our understanding of these diseases continues to evolve and new treatment strategies continue to emerge, correctly differentiating and diagnosing ...
J. De Groof +3 more
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CT and MR imaging for evaluation of cystic renal lesions and diseases.
Radiographics, 2015Cystic renal lesions are commonly encountered in abdominal imaging. Although most cystic renal lesions are benign simple cysts, complex renal cysts, infectious cystic renal disease, and multifocal cystic renal disease are also common phenomena.
Cecil G. Wood +9 more
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