Results 291 to 300 of about 10,805,577 (430)
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang+16 more
wiley +1 more source
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang+16 more
wiley +1 more source
Modeling the impact of antiretroviral therapy on HIV and related kidney diseases in Tanzania. [PDF]
Mchwampaka JP, Amadi M, Mbare NS.
europepmc +1 more source
Myotonic dystrophy and polycystic disease of the kidneys. [PDF]
Alan E H Emery+2 more
openalex +1 more source
Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao+15 more
wiley +1 more source
The role of nesfatin-1 in kidney diseases. [PDF]
Badeńska M+3 more
europepmc +1 more source
RELATIONSHIP OF DONOR AGE TO IN VITRO PRODUCTION OF FOOT-AND-MOUTH DISEASE VIRUS BY MOUSE KIDNEY CELLS [PDF]
Charles Campbell
openalex +1 more source