Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl +8 more
wiley +1 more source
Genetic etiology of inherited kidney diseases in egyptian patients: next generation sequencing identifies six novel variants. [PDF]
Elaraby NM +13 more
europepmc +1 more source
Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016 [PDF]
Al-Aly, Ziyad +9 more
core +1 more source
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee +9 more
wiley +1 more source
RNA-Based Therapies in Kidney Diseases. [PDF]
Hu L, Jin T, Zhang N, Ding J, Li L.
europepmc +1 more source
Polycystin 2 is increased in disease to protect against stress-induced cell death [PDF]
Brill, Allison L. +13 more
core +1 more source
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu +10 more
wiley +1 more source
Commemorating the National Institute of Diabetes and Digestive and Kidney Diseases' Advances in Kidney Health: 75 Years of Discovery and Impact. [PDF]
Rhee CM +3 more
europepmc +1 more source
Chronic kidney disease and the global public health agenda: an international consensus
Anna Francis +18 more
semanticscholar +1 more source

