Results 361 to 370 of about 10,805,577 (430)

Targeting endoplasmic reticulum stress: an innovative therapeutic strategy for podocyte-related kidney diseases. [PDF]

J Transl Med
Lv J, Yu H, Du S, Xu P, Zhao Y, Qi W, Wang X.   +6 more
europepmc   +1 more source

Icaritin Represses Autophagy to Promote Colorectal Cancer Cell Apoptosis and Sensitized Low‐Temperature Photothermal Therapy via Targeting HSP90‐TXNDC9 Interactions

Advanced Science, EarlyView.
Icaritin demonstrates broad antitumor effects by inhibiting colorectal cancer (CRC) cell proliferation, migration, invasion, and causing cell cycle arrest. It induces apoptosis by repressing autophagic flux through disrupting HSP90‐TXNDC9 interactions.
Dan He, Siliang Chen, Xiaoyun Wang, Xiang Wen, Changyang Gong, Lei Liu, Gu He   +6 more
wiley   +1 more source

Development of a prediction model for in-hospital mortality in immunocompromised chronic kidney diseases patients with severe infection. [PDF]

BMC Nephrol
Wang Y, Zhou Y, Huang C, Wang Y, Lou L, Zhao L, Xu S, Zheng M, Li S.   +8 more
europepmc   +1 more source

Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA

Advanced Science, EarlyView.
In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa, Rikako Sato, Mariko Konaka, Yuma Yamada, Hideyoshi Harashima, Yusuke Sato   +5 more
wiley   +1 more source

Chronic kidney diseases and inflammation research: a bibliometric analysis. [PDF]

Front Med (Lausanne)
Wang H, Chen Y, Gou Y, Yang D, Xiong L.
europepmc   +1 more source

Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer

Advanced Science, EarlyView.
A single‐cell and spatial transcriptional atlas reveals the architecture of human gastric cancer stem cell (CSC) niche and the developmental trajectory of CSCs. These CSCs interact with immunosuppressive immune cells thereby constructing immune‐suppressive niche, and inflammatory cancer‐associated fibroblast (iCAFs) to enhance stemness through ...
Guangyu Zhang, Xin Zhang, Wenting Pan, Xizhao Chen, Lingfei Wan, Chunjie Liu, Yuting Yong, Yue Zhao, Shuli Sang, Lihua Zhang, Sheng Yao, Yushu Guo, Mingmei Wang, Xinhui Wang, Guangdun Peng, Xinlong Yan, Yanchun Wang, Min Zhang   +17 more
wiley   +1 more source

Oral lactoferrin as a treatment of pediatrics' anemia resulted from chronic kidney diseases: a randomized controlled trial. [PDF]

Sci Rep
Hegazy SK, Koura MSE, Elharoun MS.
europepmc   +1 more source

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

Advanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu, Qing Ma, Yunhui Kong, Zhaoyue Wang, Minglu Xu, Xiangyi Chen, Yajuan Su, Tinghui Xiao, Qing He, Xuan Wang, Wenjun Xu, Yiling Yang, Xushu Wang, Xiaobo Li, Yanfang Liu, Shuangshuang Chen, Rui Zhao, Meng Guo, Gaowei Wang, Weida Li   +19 more
wiley   +1 more source

Scoping Review of Economic Analyses of Rare Kidney Diseases. [PDF]

Kidney Int Rep
Angell B, Wang S, Gadsden T, Moorthy M, Malik C, Barratt J, Devuyst O, Ulasi II, Gale DP, Sengupta A, Palagyi A, Jha V, Jan S.   +12 more
europepmc   +1 more source

Chronic kidney disease and the global public health agenda: an international consensus

Nature Reviews Nephrology
Anna Francis, M. Harhay, A. Ong, S. Tummalapalli, Alberto Ortiz, Agnes B. Fogo, D. Fliser, Prabir Roy-Chaudhury, Monica Fontana, M. Nangaku, Christoph Wanner, Charu Malik, A. Hradsky, Dwomoa Adu, S. Bavanandan, A. Cusumano, Laura Solá, I. Ulasi, Vivekanand Jha   +18 more
semanticscholar   +1 more source