Results 21 to 30 of about 429,733 (262)

Role of renin–angiotensin–aldosterone system inhibitors in heart failure and chronic kidney disease

Drugs in Context, 2020
Renin–angiotensin–aldosterone system (RAAS) inhibitors are the key medications for patients with heart failure and chronic kidney disease. Multiple randomized controlled trials have demonstrated their benefits in an outpatient setting for the treatment ...
Namrata Singhania, Saurabh Bansal, Shreya Mohandas, Divya P Nimmatoori, Abutaleb A Ejaz, Girish Singhania   +5 more
doaj   +1 more source

Mechanism of tonifying-kidney Chinese herbal medicine in the treatment of chronic heart failure

Frontiers in Cardiovascular Medicine, 2022
According to traditional Chinese medicine (TCM), chronic heart failure has the basic pathological characteristics of “heart-kidney yang deficiency.” Chronic heart failure with heart- and kidney-Yang deficiency has good overlap with New York Heart ...
Lizhen Chen, Dayun Yu, Shuang Ling, Jin-Wen Xu   +3 more
doaj   +1 more source

GRATITUDE TRAINING TO REDUCE THE DEPRESSION LEVEL AMONG THE PATIENTS WITH CHRONIC KIDNEY FAILURE UNDERGOING THE HEMODIALYSIS THERAPY

JIP (Jurnal Intervensi Psikologi), 2023
: The purpose of the study was to investigate the effectiveness of gratitude training on reducing depression levels among patients with chronic kidney failure undergoing hemodialysis therapy. The study used a single-subject experimental design with the A-
Ahmad Fikry Ghazali, Qurotul Uyun, Khairul Anwar Mastor   +2 more
doaj   +1 more source

L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China

Frontiers in Public Health
BackgroundPrevious studies have shown that the triglyceride glucose-body mass index (TyG-BMI) is associated with cardiovascular disease, stroke, and cognition. Its relationship with mental health remains underexplored.
Yanqin Li, Qi Gao, Qi Gao, Fan Luo, Yuxin Lin, Ruqi Xu, Pingping Li, Yuping Zhang, Jiao Liu, Hongrui Zhan, Licong Su   +10 more
doaj   +1 more source

Management of hyperkalaemia in acute kidney injury in a heart failure patient with patiromer

ESC Heart Failure, 2020
Aims One prevalent comorbidity of chronic heart failure (CHF) is chronic kidney disease(CKD). Hyperkalemia is associated with both CHF and CKD, which often leads to withdrawal of heart failure medications in clinical praxis. Methods and results A patient
Jonathan Slawik, Juliane Dederer, Ingrid Kindermann, Michael Böhm   +3 more
doaj   +1 more source

APOL1 Genotype, Proteinuria, and the Risk of Kidney Failure: A Secondary Analysis of the AASK (African American Study of Kidney Disease and Hypertension) and CRIC (Chronic Renal Insufficiency Cohort) StudiesPlain-Language Summary

Kidney Medicine, 2022
Rationale & Objective: Patients with a high-risk Apolipoprotein L1 (APOL1) genotype are more likely to develop chronic kidney disease and kidney failure. It is unclear whether this increased risk is entirely mediated by the development of proteinuria.
Anthony Nguyen, Sze-chuan Suen, Eugene Lin   +2 more
doaj   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Frequency-reduction strategy of roxadustat in patients undergoing peritoneal dialysis: a multi-center retrospective cohort study

Frontiers in Medicine
BackgroundAlthough dose reduction is the guideline-recommended tapering strategy for roxadustat to maintain target hemoglobin levels in peritoneal dialysis (PD) patients during the maintenance phase, reducing the administration frequency represents ...
Xi Mi, Xi Mi, Xi Mi, Xi Mi, Xi Mi, Guanying Lin, Guanying Lin, Guanying Lin, Guanying Lin, Guanying Lin, Yijing Fang, Yijing Fang, Yijing Fang, Yijing Fang, Yijing Fang, Lu Zhu, Yanhong Lin, Yanhong Lin, Yanhong Lin, Yanhong Lin, Yanhong Lin, Tingting Zhang, Tingting Zhang, Tingting Zhang, Tingting Zhang, Tingting Zhang, Xiaohong Zhong, Xiaohong Zhong, Xiaohong Zhong, Xiaohong Zhong, Xiaohong Zhong, Xiaoyan Su, Xiaoyan Su, Xianrui Dou, Jun Ai, Jun Ai, Jun Ai, Jun Ai, Jun Ai   +38 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source