Results 151 to 160 of about 2,803,576 (301)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Association of UACR and UPCR with kidney failure: a pooled analysis of clinical trials. [PDF]

Nephrol Dial Transplant
Mepschen M, Vos R, Herrington W, Provenzano M, Beernink JM, La Manna G, Gansevoort RT, Heerspink HJL.   +7 more
europepmc   +1 more source

Hepatic Failure and the Kidney

Gastroenterology, 1966
openaire   +2 more sources

The Mind From Within: Visceral Roots of Human Cognition

Advanced Science, EarlyView.
The physiological activity of visceral organs, such as the heart, the lungs, and the gut, is surprisingly linked to many sophisticated mental operations, such as remembering the past, being aware of ourselves, making choices, and forging social bonds.
Alessandro Monti, Salvatore Maria Aglioti   +1 more
wiley   +1 more source

Causal Effects of Early Discontinuation of Proton Pump Inhibitors on Kidney Failure. [PDF]

Kidney Int Rep
Kawano Y, Oka T, Sakaguchi Y, Kadono H, Uwatoko R, Fukuda S, Doi Y, Hashimoto N, Kusunoki Y, Yamamoto S, Yamato M, Yamamoto R, Matsui I, Mizui M, Kaimori JY, Isaka Y.   +15 more
europepmc   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Implementing a Protocol for Incremental Hemodialysis in Incident Patients With Kidney Failure: A Quality Improvement Initiative. [PDF]

Can J Kidney Health Dis
Messina A, Taha A, Sanchez-Allakhverdieva A, Laurier N, Tom A, Tan V, Filteau N, McKinnon J, Blum D, Weber C, Trinh E.   +10 more
europepmc   +1 more source

Idarucizumab Dosing in Kidney Failure [PDF]

American Journal of Kidney Diseases, 2018
Luke Yip, Jou-Fang Deng
openaire   +2 more sources

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Capacity for the management of kidney failure in the International Society of Nephrology North and East Asia region: report from the 2023 ISN Global Kidney Health Atlas (ISN-GKHA)

Globally, there remain significant disparities in the capacity and quality of kidney care, as evidenced by the third edition of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA).
Hirakawa, Yosuke, Yu, Xueqing, Tonelli, Marcello, Cho, Yeoungjee, Yanagita, Motoko, Kashihara, Naoki, Sozio, Stephen M, Zaidi, Deenaz, Johnson, David W, Damster, Sandrine, Ueda, Seiji, Petrova, Anna, Saad, Syed, Sakajiki, Aminu Muhammad, Tang, Sydney C W, Jindal, Kailash, Yeung, Emily K, Ekrikpo, Udeme E, Irish, Georgina, Donner, Jo Ann, Divyaveer, Smita, Ibrahim, Kwaifa Salihu, Yang, Jihyun, Yang, Chih Wei, Amouzegar, Atefeh, Tiv, Sophanny, Okpechi, Ikechi G, Lalji, Rowena, Chen, Hung Chun, Nie, Jing, Jha, Vivekanand, Riaz, Parnian, Arruebo, Silvia, Houston, Ghenette, See, Emily, Neuen, Brendon L, Davison, Sara N, Maruyama, Shoichi, Tungsanga, Somkanya, Cai, Guangyan, Wainstein, Marina, Wang, Angela Yee Moon, Davids, M Razeen, Liu, Bi Cheng, Olanrewaju, Timothy O, Ghimire, Anukul, Diongole, Hassane M, Fukami, Kei, Ethier, Isabelle, Bello, Aminu K, Fung, Wing-Shing, Winston, Nishiyama, Akira, Cheng, Yuk Lun, Nalado, Aisha M, Park, Hyeong Cheon, Osman, Mohamed A, Doi, Kent, Zhang, Hong, Chang, Jer Ming, Levin, Adeera, Kelly, Dearbhla M, Viecelli, Andrea, Ye, Feng, Htay, Htay, Zhou, Lili, Nangaku, Masaomi, Imaizumi, Takahiro, Suzuki, Yusuke, Caskey, Fergus J, Malik, Charu   +69 more
core   +1 more source