Results 291 to 300 of about 1,022,396 (355)

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source

Genetic Terminal Complement Deficiency in Israeli Bedouins With Kidney Failure. [PDF]

Kidney Int Rep
Chowers G, Ben-Ruby D, Atias-Varon D, Shlomovitz O, Slabodnik-Kaner K, Kagan M, Avayou S, Romanjuk E, Rogachev B, Haviv YS, Birk OS, Hadar N, Bathish Y, Barshack I, Volkov A, Avivi C, Pavlovsky A, Haskin O, Simon AJ, Glick-Saar E, Ostrovsky A, Assi M, Schreiber R, Levin D, Yagil Y, Awawdeh M, Skorecki K, Dominissini D, Shnaider A, Vivante A.   +29 more
europepmc   +1 more source

Deoxynivalenol Exposure Leads to Abnormal Renal Tubular Autophagy Flow

Advanced Science, EarlyView.
DON exposure disrupts the initiation of renal autophagy by inhibiting the formation of autophagosomes, thereby impairing mitochondrial degradation. Damaged mitochondria increase oxidative stress, reduce ferroptosis resistance, and cause lysosomal Fe2⁺ accumulation, further disrupting autophagy.
Hao Chen, Xintong Zhou, Jun Ma
wiley   +1 more source

Prediction Model for Risk of Death in Elderly Critically Ill Patients with Kidney Failure. [PDF]

Medicina (Kaunas)
Zeng J, Ye F, Du J, Zhang M, Yang J, Wu Y.   +5 more
europepmc   +1 more source

Utility of a water-sparing approach for reducing dialysate flow rates in hospitalized patients with kidney failure. [PDF]

Int J Artif Organs
Parikh A, Drake K, Woda C, D'Alessandri-Silva C, Aragon M.   +4 more
europepmc   +1 more source

Predicting Postoperative Cardiac Events and Mortality for People with Kidney Failure Having Noncardiac Surgery: An External Validation Study. [PDF]

Kidney360
Pabla GS, Tangri N, Whitlock RH, Ferguson T, Harrison TG.   +4 more
europepmc   +1 more source

Distinguishing Among Causes of Death for Patients with Kidney Failure on Hemodialysis. [PDF]

Kidney360
Tran M, Xu CA, Wilson J, Ephraim PL, Shafi T, Weiner DE, Goldstein BA, Scialla JJ, Scialla JJ, Comparative Effectiveness Studies in Dialysis Patients Group.   +9 more
europepmc   +1 more source

Gender Differences in Kidney Failure Incidence in Australia: A Registry Study.

Am J Nephrol
McDonald S, Stallard BC, McDonald SP.
europepmc   +1 more source

Mortality Risk Prediction Models for People With Kidney Failure: A Systematic Review.

JAMA Netw Open
Jarrar F, Pasternak M, Harrison TG, James MT, Quinn RR, Lam NN, Donald M, Elliott M, Lorenzetti DL, Strippoli G, Liu P, Sawhney S, Gerds TA, Ravani P.   +13 more
europepmc   +1 more source

Plasma and Urinary KIM-1 in Chronic Kidney Disease: Prognostic Value, Associations with Albuminuria, and Implications for Kidney Failure and Mortality.

Am J Nephrol
McDonnell T, Söderberg M, Taal MW, Vuilleumier N, Kalra PA, NURTuRE-CKD academic steering group.   +5 more
europepmc   +1 more source