Results 321 to 330 of about 4,640,867 (405)

Challenges in the clinical use of digital tools in healthcare: barriers and blueprint for Kidney Failure Risk Equation implementation (Preprint)

Rupert Major, Javeria Peracha, Ziva Frangez, Anne Dreyer, Patrick Rueegger, Chaohui Guo, Paul Cockwell, Kristin Veighey   +7 more
openalex   +1 more source

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

Genetic and metabolomic pathways linking frailty, chronic kidney disease, and kidney failure: a Mendelian randomization and multi-omics analysis. [PDF]

Ren Fail
Chen Y, Wang K, Zhang X, Yang F, Liu T, Cheng A, Guan Y, Zhong J, Meng J, Zhang X, Liao G.   +10 more
europepmc   +1 more source

Functional kidney state in patients with decompensated heart failure: annual outpatient follow-up results

Zhanna Kobalava, Natalia Kontareva, Yulia Khruleva, Robinson Tsimine Andriamanohery, L. V. Karapetyan, С. А. Галочкин   +5 more
openalex   +2 more sources

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

REMOVAL OF MIDDLE MOLECULES WITH HEMODIAFILTRATION PLUS HEMOADSORPTION IN KIDNEY FAILURE PATIENTS

Thiago Reis, Maria Gabriela Guimarães, Júlia Resende de Andrade, Miguel Ângelo Goés, Andréia Watanabe, Claudio Ronco, Francisco de Assis Rocha Neves, Bruno Biluca, Antônio Luiz Junqueira Almeida, Antônio Luiz Junqueira Almeida⁷   +9 more
openalex   +1 more source

Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications

Advanced Science, EarlyView.
This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss, Vasiliki Gkouzioti, Wuliji Hanggai, Friso Kahler, Elena Aprea, Qi Jia, Jean‐Philippe Frimat, Ekkes Brück, Clementine M. Boutry   +8 more
wiley   +1 more source

Applicability of the Framingham Risk Score in predicting mortality among kidney failure patients: an international analysis. [PDF]

Clin Kidney J
Chen Z, Li X, Qureshi AR, Wang R, Jiang H, Heimbürger O, Barany P, Chen J, Stenvinkel P, Lindholm B.   +9 more
europepmc   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Kidney failure in the course of focal segmental glomerulonephritis in a patient after alloHSCT - a case study and review of the literature. [PDF]

J Nephrol
Kaszyńska A, Kępska-Dzilińska M, Karakulska-Prystupiuk E, Perkowska-Ptasińska A, Małyszko J.   +4 more
europepmc   +1 more source