Results 1 to 10 of about 1,000,243 (269)
Effects of the Long-term Treatment of Proton Pump Inhibitors on the Function of Kidney and Liver in Laboratory Female Rats [PDF]
Archives of Razi Institute, 2021 Proton pump inhibitors (PPIs) are a group of medications effectively used to inhibit gastric acid secretion and to treat many acid-related disorders, including gastroesophageal reflux disease and other gastric disorders.
S. M. J AL-Hadrawy, Z. S Mahdi AL-Turfi
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How Adequate is the Adequate Kidney Function for Clinical Trial Enrollment of Novel Anticancer Drugs? [PDF]
Research in Oncology, 2020 Excessively restrictive eligibility criteria hinder the enrollment of cancer patients to clinical trials. Those patients are supposed to represent the range of characteristics of the overall population with particular cancer.
Nehal Gamal, Kyrillus S. Shohdy
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Frontiers in Nutrition, 2022 BackgroundAlthough many molecular studies have tried to explore the relationship between vitamin D metabolism and kidney function, the association between 25-hydroxyvitamin D [25(OH)D] and kidney function is still controversial. Previous studies reported
Jiwen Geng +15 more
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eLife, 2020 Abundant APOBEC3 (A3) deaminase-mediated mutations can dominate the mutational landscape (‘mutator phenotype’) of some cancers, however, the basis of this sporadic vulnerability is unknown.
Birong Shen +5 more
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Frontiers in Pediatrics, 2022 ObjectiveHyaluronic acid (HA) and N-terminal propeptide of type III procollagen (PIIINP) are two non-invasive biomarkers of liver fibrosis in non-alcoholic fatty liver disease (NAFLD).
Antonella Mosca +10 more
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Feasible kidney donation with living marginal donors, including diabetes mellitus
Immunity, Inflammation and Disease, 2021 Objectives To compare the donor outcomes of living donor kidney transplantation between standard donors (SDs) and marginal donors (MDs) including diabetic patients (MD + DM).
Kasumi Yoshinaga +19 more
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Repair of naturally occurring mismatches can induce mutations in flanking DNA
eLife, 2014 ‘Normal’ genomic DNA contains hundreds of mismatches that are generated daily by the spontaneous deamination of C (U/G) and methyl-C (T/G). Thus, a mutagenic effect of their repair could constitute a serious genetic burden.
Jia Chen +2 more
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The NADPH Oxidase Isoform 1 Contributes to Angiotensin II-Mediated DNA Damage in the Kidney
Antioxidants, 2020 In higher concentrations, the blood pressure regulating hormone angiotensin II leads to vasoconstriction, hypertension, and oxidative stress by activating NADPH oxidases which are a major enzymatic source of reactive oxygen species (ROS).
Anna Zimnol +4 more
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BMC Nephrology, 2018 Background Immunoglobulin heavy-and-light-chain amyloidosis (AHL amyloidosis) is a newly established disease entity where both the immunoglobulin heavy-chain and light-chain compose amyloid fibrils. The immunoglobulins responsible for the amyloid fibrils
Shun Manabe +6 more
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Toxics, 2020 Cadmium (Cd) is a toxic metal associated with adverse health effects, including kidney injury or disease. The aims of this study were to estimate dietary Cd exposure during childhood, and to evaluate the association of early-life dietary Cd with ...
Edna Rodríguez-López +12 more
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