Results 111 to 120 of about 12,427,323 (309)

A Multiparametric Assay Platform for Simultaneous In Vivo Assessment of Pronephric Morphology, Renal Function and Heart Rate in Larval Zebrafish

Cells, 2020
Automated high-throughput workflows allow for chemical toxicity testing and drug discovery in zebrafish disease models. Due to its conserved structural and functional properties, the zebrafish pronephros offers a unique model to study renal development ...
Petrus J. Steenbergen, Jana Heigwer, Gunjan Pandey, Burkhard Tönshoff, Jochen Gehrig, Jens H. Westhoff   +5 more
doaj   +1 more source

Comparative Performance of Creatinine-Based GFR Estimation Equations in Exceptional Longevity: The Rugao Longevity and Ageing Study [Erratum]

Clinical Interventions in Aging, 2020
Wang M, Sun X, Ni L, et al. Clin Interv Aging.  2020;15:733– 742.The authors have advised that the Funding statement was missed on page 741 of the published paper.
Wang M, Sun X, Ni L, Zhang M, Zhang J, Ye G, Jin L, Wang X, Chen J   +8 more
doaj  

Determining cellular and biochemical function of a novel adhesion molecule in kidneys. [PDF]

, 2016
Acute kidney injury is an abrupt loss of kidney function that develops in short time with limited effective treatments other than kidney transplantation. We have identified TMIGD1 (Transmembrane immuno- globulin domain 1) as a novel receptor expressed in
Arafa, Emad
core   +1 more source

A comparison of the effects of oral vs. intravenous hydration on subclinical acute kidney injury: a protocol of a randomised controlled trial [PDF]

, 2017
Background: Optimal treatment for established renal failure is living donor kidney transplantation. However this pathway exposes healthy individuals to significant reduction in nephron mass via major surgical procedure.
Aitken, Emma, Clancy, Marc, Ghita, Ryan, Mackinnon, Shona   +3 more
core   +1 more source

Coffee Consumption and Kidney Function: A Mendelian Randomization Study.

American Journal of Kidney Diseases, 2019
RATIONALE & OBJECTIVE Chronic kidney disease (CKD) is a leading cause of morbidity and mortality worldwide, with limited strategies for prevention and treatment.
O. Kennedy, N. Pirastu, Robin Poole, J. Fallowfield, P. Hayes, Eryk J. Grzeszkowiak, M. Taal, James F. Wilson, J. Parkes, P. Roderick   +9 more
semanticscholar   +1 more source

The Kidney: Structure and Function in Health and Disease. [PDF]

, 1951
Harry Goldblatt
openalex   +2 more sources

Thermal imprinting modifies adult stress and innate immune responsiveness in the teleost sea bream [PDF]

, 2017
The impact of thermal imprinting on the plasticity of the hypothalamic-pituitary-interrenal (HPI) axis and stress response in an adult ectotherm, the gilthead sea bream (Sparus aurata, L.), during its development was assessed.
A Costa, Rita, Andree, Karl B., Cardoso, João CR, Estevez, Alicia, Gisbert, Enric, Mateus, Ana, Power, Deborah   +6 more
core   +1 more source

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

Nature Communications, 2018
Chronic kidney disease (CKD) affects ~10% of the global population, with considerable ethnic differences in prevalence and aetiology. We assemble genome-wide association studies of estimated glomerular filtration rate (eGFR), a measure of kidney function
A. Morris, T. Le, Haojia Wu, A. Akbarov, Peter J. van der Most, G. Hemani, G. Smith, A. Mahajan, K. Gaulton, G. Nadkarni, A. Valladares-Salgado, N. Wacher-Rodarte, J. Mychaleckyj, Nicole D Dueker, Xiuqing Guo, Y. Hai, J. Haessler, Y. Kamatani, A. Stilp, G. Zhu, J. Cook, J. Ärnlöv, S. Blanton, M. D. de Borst, E. Bottinger, T. Buchanan, S. Cechova, F. Charchar, Pei-Lun Chu, J. Damman, James M. Eales, A. Gharavi, V. Giedraitis, A. Heath, E. Ipp, K. Kiryluk, H. Kramer, M. Kubo, A. Larsson, C. Lindgren, Yingchang Lu, P. Madden, G. Montgomery, G. Papanicolaou, L. Raffel, R. Sacco, Elena Sanchez, H. Stark, J. Sundstrom, K. Taylor, A. Xiang, A. Živković, L. Lind, E. Ingelsson, N. Martin, J. Whitfield, Jianwen Cai, C. Laurie, Y. Okada, K. Matsuda, C. Kooperberg, Y. Chen, T. Rundek, S. Rich, R. Loos, E. Parra, M. Cruz, J. Rotter, H. Snieder, M. Tomaszewski, B. Humphreys, N. Franceschini   +71 more
semanticscholar   +1 more source

The relationship between P2X4 and P2X7: a physiologically important interaction? [PDF]

, 2013
Purinergic signaling within the kidney is becoming an important focus in the study of renal health and disease. The effectors of ATP signaling, the P2Y and P2X receptors, are expressed to varying extents in and along the nephron.
Birch, Rebecca E, Craigie, Eilidh, Unwin, Robert J, Wildman, Scott S.P.   +3 more
core   +3 more sources

Trajectories of Kidney Function in Children with Reduced Kidney Function

, 2018
Little is known about the progression of chronic kidney disease (CKD) during the emerging adulthood period in patients with pediatric onset CKD cared for in primary care. We performed a retrospective cohort study using administrative data from The Health Improvement Network Database to determine the natural history of CKD, the impact of the emerging ...
openaire   +3 more sources