Results 211 to 220 of about 1,000,243 (269)

Environmental Exposure to Cadmium and Lead Exacerbates Kidney Function in People with Diabetes. [PDF]

J Xenobiot
Satarug S, Vesey DA, Khamphaya T, Waeyeng D, Yimthiang S.   +4 more
europepmc   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Impairment of Kidney Function in Patients with Chronic Coronary Syndromes. [PDF]

J Clin Med
Charkiewicz-Szeremeta K, Sawicka-Śmiarowska E, Czarnecka D, Dubatówka M, Gąsior Z, Hryszko T, Jankowski P, Knapp M, Kosior DA, Kubica A, Mickiewicz K, Pająk A, Rajzer M, Styczkiewicz M, Wolfshaut-Wolak R, Kamiński KA.   +15 more
europepmc   +1 more source

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

Advanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin, Hanieh Mohammad Hashemi, Kimia Asadi Jozani, Anushree Chakravarty, Sonya Kouthouridis, Jessica Bonanno, Nicky Anvari, Shravanthi Rajasekar, Feng Zhang, Richard Y. Cheng, Narendra Kumar Singh, Luis Miguel Medina, Marc Durante, Yufang He, Boyang Zhang   +14 more
wiley   +1 more source

Acidosis at Diagnosis of Type 1 Diabetes Mellitus: Relation With Kidney Function. [PDF]

Pediatr Diabetes
Guarino S, Iafusco D, Di Sessa A, Tirelli P, Rivetti G, Ippolito G, Bartiromo M, Cirillo G, Zanfardino A, Miraglia Del Giudice E, Marzuillo P.   +10 more
europepmc   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Association of Posttransplant Kidney Function With Patient Reported Outcomes: A Single Center's Experience Over Nearly Two Decades. [PDF]

Clin Transplant
Thorne P, Binari LA, Rega SA, Kochar G, Forbes RC, Pinson CW, Feurer ID, Concepcion BP.   +7 more
europepmc   +1 more source