Results 61 to 70 of about 12,427,323 (309)
While hypothyroidism increases serum creatinine (Cr) levels, it is uncertain whether the elevation is mediated via a decline in the glomerular filtration rate (GFR) or the reflection of enhanced Cr production from the muscles or both.
Natsumi Matsuoka-Uchiyama+8 more
doaj +1 more source
An emerging protagonist: Sodium Glucose Co-transporters (SGLTs) as a burgeoning target for the treatment of diabetes mellitus [PDF]
Contemporary therapies to rationalize the hyperglycaemia in type 2 diabetes mellitus (T2DM) generally involve insulin-dependent mechanisms and lose their effectiveness as pancreatic b-cell function decreases to a greater extent. The kidney emerges out as
Danish Ahmed+3 more
core +2 more sources
Pathfinder cells provide a novel therapeutic intervention for acute kidney injury [PDF]
Pathfinder cells (PCs) are a novel class of adult-derived cells that facilitate functional repair of host tissue. We used rat PCs to demonstrate that they enable the functional mitigation of ischemia reperfusion (I/R) injury in a mouse model of renal ...
Alan MacIntyre+11 more
core +1 more source
Hypernatremia and Acute Kidney Injury in Exclusive Breast Fed Babies-Time to Reconsider! [PDF]
Introduction: Hypernatremia in breast fed babies is not very commonly reported. But incidence seems to be increasing. Exact pathophysiology is not clear but hypothesised to be due to relative lactation failure in early postnatal period especially in ...
Shobha Sharma+4 more
doaj +1 more source
Emerging key roles for P2X receptors in the kidney [PDF]
P2X ionotropic non-selective cation channels are expressed throughout the kidney and are activated in a paracrine or autocrine manner following the binding of extracellular ATP and related extracellular nucleotides. Whilst there is a wealth of literature
Birch, R. E.+3 more
core +2 more sources
Context Panax notoginseng (Burk.) F.H. Chen (Araliaceae) preparations (PNP) are traditional Chinese medicines used as adjuvant therapeutics for diabetic kidney disease (DKD).
Xiuge Tang+7 more
doaj +1 more source
Background Pimobendan might have favorable effects on renal function but this has not been well‐studied in dogs with myxomatous mitral valve disease (MMVD). Objectives Determine the effects of standard‐dose (SD_pimo) and high‐dose pimobendan (HD_pimo) on
Joanna L. Kaplan+6 more
doaj +1 more source
Non-contrast renal magnetic resonance imaging to assess perfusion and corticomedullary differentiation in health and chronic kidney disease [PDF]
AIMS Arterial spin labelling (ASL) MRI measures perfusion without administration of contrast agent. While ASL has been validated in animals and healthy volunteers (HVs), application to chronic kidney disease (CKD) has been limited. We investigated the
Delles, Christian+9 more
core +1 more source
Kidney Function Assessment in African American Patients: A Narrative Review for Pharmacists
Recent recognitions of longstanding societal inequity in kidney function assessments have prompted the call to eliminate race as part of the algorithm to assess estimated glomerular filtration rate (eGFR).
Dhakrit Rungkitwattanakul+3 more
doaj +1 more source
Primary Renal Lymphoma Presenting as End-Stage Renal Disease. [PDF]
Primary renal lymphoma is a rare entity, even more so in children. Children with primary renal lymphoma present with variable clinical features such as constitutional signs and symptoms, acute kidney injury, palpable abdominal masses, and gross hematuria.
Butani, Lavjay, Ducore, Jonathan
core +3 more sources