Results 61 to 70 of about 1,603,200 (360)

The Role of Glomerular Epithelial Injury in Kidney Function Decline in Patients With Diabetic Kidney Disease in the TRIDENT Cohort

Kidney International Reports, 2021
Introduction: Although diabetic kidney disease (DKD) is responsible for more than half of all chronic and end-stage kidney disease (ESKD), the association of light (LM) and electron microscopic (EM) structural changes with clinical parameters and ...
Matthew B. Palmer, Amin Abedini, Casey Jackson, Shira Blady, Shatakshee Chatterjee, Katie Marie Sullivan, Raymond R. Townsend, Jens Brodbeck, Salem Almaani, Anand Srivastava, Rupali Avasare, Michael J. Ross, Amy K. Mottl, Christos Argyropoulos, Jonathan Hogan, Katalin Susztak   +15 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Kidney after nonrenal transplantation-the impact of alemtuzumab induction [PDF]

, 2009
BACKGROUND.: Calcineurin inhibitor nephrotoxicity in nonrenal allograft recipients can lead to end-stage renal disease and the need for kidney transplantation. We sought to evaluate the role of alemtuzumab induction in this population.
Amit Basu, Calne, Claire Morgan, Deanna Blisard, Demetrius Ellis, Eghtesad, Geoffrey Kurland, George Mazariegos, Henkie P. Tan, Igor Dvorchik, J Wallis Marsh, Jerry McCauley, Kareem Abu-Elmagd, Kenneth R. McCurry, Kirk, Knechtle, Ojo, Parmjeet S. Randhawa, Ron Shapiro, Shapiro, Shapiro, Shapiro, Steven Webber, Stuart, Tan, Thomas E. Starzl, Vivek Sharma, Waldmann   +27 more
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Thermal imprinting modifies adult stress and innate immune responsiveness in the teleost sea bream [PDF]

, 2017
The impact of thermal imprinting on the plasticity of the hypothalamic-pituitary-interrenal (HPI) axis and stress response in an adult ectotherm, the gilthead sea bream (Sparus aurata, L.), during its development was assessed.
A Costa, Rita, Andree, Karl B., Cardoso, João CR, Estevez, Alicia, Gisbert, Enric, Mateus, Ana, Power, Deborah   +6 more
core   +1 more source

Perfluoroalkyl substances and kidney function in chronic kidney disease, anemia, and diabetes

Diabetes, Metabolic Syndrome and Obesity, 2018
Baqiyyah N Conway,1,2 Ashley N Badders,1,3 Tina Costacou,4 John M Arthur,5 Kim E Innes1 1Department of Epidemiology, School of Public Health, West Virginia University, Morgantown, WV, USA; 2Department of Community Health, School of Rural and Community ...
Conway BN, Badders AN, Costacou T, Arthur JM, Innes KE   +4 more
doaj  

Metabolic Effects of Sodium Thiosulfate During Resuscitation from Trauma and Hemorrhage in Cigarette-Smoke-Exposed Cystathionine-γ-Lyase Knockout Mice

Biomedicines
Background: Acute and chronic pre-traumatic cigarette smoke exposure increases morbidity and mortality after trauma and hemorrhage. In mice with a genetic deletion of the H2S-producing enzyme cystathione-γ-lyase (CSE−/−), providing exogenous H2S using ...
Maximilian Feth, Felix Hezel, Michael Gröger, Melanie Hogg, Fabian Zink, Sandra Kress, Andrea Hoffmann, Enrico Calzia, Ulrich Wachter, Peter Radermacher, Tamara Merz   +10 more
doaj   +1 more source

A Multiparametric Assay Platform for Simultaneous In Vivo Assessment of Pronephric Morphology, Renal Function and Heart Rate in Larval Zebrafish

Cells, 2020
Automated high-throughput workflows allow for chemical toxicity testing and drug discovery in zebrafish disease models. Due to its conserved structural and functional properties, the zebrafish pronephros offers a unique model to study renal development ...
Petrus J. Steenbergen, Jana Heigwer, Gunjan Pandey, Burkhard Tönshoff, Jochen Gehrig, Jens H. Westhoff   +5 more
doaj   +1 more source

The renal function in men with hypertension in conditions of purine and carbohydrate metabolism disorders

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
Aim. To assess the condition of renal function in hypertensive men in conditions of disorders of purine and carbohydrate metabolism Material and methods.
O. V. Dudko, M. Yu. Kolesnyk
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source