Results 191 to 200 of about 911,122 (332)

Inhibition of Human Aldehyde Reductase by Drugs for Testing the Function of Liver and Kidney.

, 1999
M Shinoda, Shinichi MORI, Syunichi Shintani, Syuhei Ishikura, Akira Hara   +4 more
openalex   +2 more sources

Analytical validation of a multi-biomarker algorithmic test for prediction of progressive kidney function decline in patients with early-stage kidney disease [PDF]

, 2021
Patricia Connolly, Sharon Stapleton, Gohar Mosoyan, Ilya Fligelman, Ya-Chen Tonar, Fergus Fleming, Michael Donovan   +6 more
openalex   +1 more source

Biomimetic Nanomedicines Deliver Naringin for Enhanced Acute Liver Failure Therapy via Balanced Regulation of Hepatocyte Oxidative Stress and Kupffer Cell Inflammation

Advanced Functional Materials, EarlyView.
A biomimetic nanomedicine (RBLN) constructed by loading natural antioxidants to clinically used layered double hydroxide nanoparticles is surface coated with fresh or senescent red blood cell membrane for balanced drug delivery to hepatocytes and KCs, thereby simultaneously alleviating liver oxidant stress and inflammation for effective drug‐induced ...
Jiahui Shao, Maoze Wang, Jinling Huang, Yu Wang, Jing Zhao, Ran Wang, Zhi Ping Xu, Jianping Jiang, Lingxiao Zhang   +8 more
wiley   +1 more source

An observational 3-year follow-up study for postoperative renal function changes assessed by 99 mTc-DTPA scintigraphy and predictive factors after miniaturized percutaneous nephrolithotomy and retrograde intrarenal surgery

BMC Urology
Background This study aims to investigate changes in relative renal function three years after miniaturized percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) and to identify significant predictors associated with renal ...
Hyomyoung Lee, Yerzhan Sharapatov, Hyeji Park, Christine Joy Castillo, Majed Alharthi, Mohammad Zogan, Sung Yong Cho   +6 more
doaj   +1 more source

Evaluating kidney function using a point-of-care creatinine test in Ugandan children with severe malaria: a prospective cohort study [PDF]

, 2021
Anthony Batte, Kristin Murphy, Ruth Namazzi, Katrina Co, Robert O. Opoka, John M. Ssenkusu, Chandy C. John, Andrea L. Conroy   +7 more
openalex   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

Advanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song, Valentin A. Milichko, Ziqiao Ding, Wen Li, Bei Kang, Yunsheng Dou, Sona Krizkova, Zbynek Heger, Nan Li   +8 more
wiley   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Biochemical Assessments of Thyroid Profile and Renal Function Test in Chronic Kidney Disease [PDF]

, 2023
S. Shrivastava, Naveen Kumar Khare
openalex   +1 more source

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Precision Photothermal Therapy at Mild Temperature: NIR‐II Imaging‐Guided, H2O2‐Responsive Stealth Nanobomb

Advanced Healthcare Materials, EarlyView.
The new generation nanobomb, termed the stealth nanobomb, is fabricated through self‐assembly using a polymeric carbon monoxide carrier (PLGA(CO)), small molecule near‐infrared‐active agents (2TT‐OC46B), and phospholipid polyethylene glycol (DSPE‐mPEG2000). The stealth nanobomb can circulate in the bloodstream and specifically target pancreatic cancer,
Gongcheng Ma, Qihang Ding, Yue Wang, Zhiwei Zhang, Yuding Zhang, Hui Shi, Lintao Cai, Ping Gong, Pengfei Zhang, Zhen Cheng, Jong Seung Kim   +10 more
wiley   +1 more source