Results 271 to 280 of about 911,122 (332)

Enhanced Epithelial Cell Uptake of Glycol Chitosan‐Coated PLGA Nanoparticles for Oral Drug Delivery

Advanced Therapeutics, EarlyView.
Here, glycol chitosan (GC)‐coated PLGA NPs are developed to enhance oral drug delivery by enabling dual‐pathway endocytosis via clathrin‐ and caveolae‐mediated mechanisms. Alginate layering coating on GC‐PLGA further improves oral insulin delivery, achieving sustained glucose reduction in diabetic mice.
Huiwen Pang, Wenxuan Yu, Youzhi Wu, Xuqiang Nie, Guojun Huang, Zhi Ping Xu, Chen Chen, Felicity Y. Han   +7 more
wiley   +1 more source

Hydrophobin‐Coated Echogenic Microbubbles for Molecular Targeting of Tumor Cells

Advanced Science, EarlyView.
Echogenic microbubbles based on hydrophobin and corresponding fusion protein (HFBI‐domZ) are developed as contrast agents for cancer diagnostics. Hydrophobin provides high stabilization of encapsulated perfluoro‐n‐butane, and fusion proteins allow further versatile functionalization with antibodies. In‐vitro experiments indicate that these microbubbles
Hedar H. Al‐Terke, Grégory Beaune, Muhammad Junaid, Jani Seitsonen, Arja Paananen, Pierangelo Metrangolo, Jaakko V. I. Timonen, Jussi Joensuu, Robin H. A. Ras   +8 more
wiley   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Kidney function tests; comparative study of kidney function tests.

Revista medica de Chile, 2010
L, CORONA T, A, GARRETON S
openaire   +1 more source

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FRACTIONAL KIDNEY FUNCTION TESTS

Journal of the American Medical Association, 1928
When Cushny crystallized the idea in regard to kidney physiology into the so-called modern theory of urine formation, he gave great impetus to the better understanding of all renal physiology. Richards and his co-workers with the capillary pipet have been able to supply existing theories in regard to urine formation with the foundation of experimental ...
openaire   +2 more sources

KIDNEY, TESTS OF FUNCTION OF

1979
Publisher Summary This chapter discusses the tests of function of kidney. Kidney is an important organ for maintaining the chemical composition of the body within narrow limits. The glomerulus is a passive filter, allowing fluid of the same composition as extracellular fluid to pass into the tubular lumen: thus, the filtrate contains very little ...
openaire   +2 more sources

Thyroid function tests in acute kidney injury

Journal of Nephrology, 2012
The aim of this study was to analyze the prevalence, clinical significance and prognostic implications of alterations in thyroid function tests (TFTs) in patients with acute kidney injury (AKI).A prospective study was carried out in patients hospitalized for AKI for 2 consecutive years.
María J. Arias, Juan J. Díez, María Auxiliadora Bajo, Rafael Selgas, Cristina Vega-Cabrera, Gloria del Peso, Teresa Olea, Pedro Iglesias, M. Heras   +8 more
openaire   +3 more sources

Hydrocarbon exposure, hypertension and kidney function tests

International Archives of Occupational and Environmental Health, 1990
Control and hydrocarbon exposed workers participated in a cross-sectional study about the nephrotoxicity of chronic hydrocarbon exposure. Different markers of glomerular and tubular function as well as the celluria were examined and compared. The results show that the interaction between hypertension and hydrocarbon exposure has an influence on the ...
F. Rey, Claudia Mazzocato, Michel P Guillemin, J. Pilliod, Philippe Hotz, M A Boillat, Michèle Berode, Alfred Bernard   +7 more
openaire   +3 more sources

Kidney Function Tests and Urinalysis

2009
The most common surrogates of kidney function are serum creatinine, urea, cystatin C; however, these all have limitations, most important of which is that they do not accurately reflecting real-time dynamic changes in glomerular filtration rate (GFR) that occur in acute kidney injury (AKI) The Cockcroft-Gault and Modification of Diet in Renal Disease ...
openaire   +2 more sources