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Isogenic Kidney Glomerulus Chip Engineered from Human Induced Pluripotent Stem Cells.
Journal of Visualized Experiments, 2022Chronic kidney disease (CKD) affects 15% of the U.S. adult population, but the establishment of targeted therapies has been limited by the lack of functional models that can accurately predict human biological responses and nephrotoxicity.
Yasmin Roye, Samira Musah
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Guarding the glomerulus: Diabetes and the kidney
Independent Nurse, 2020Beverley Bostock explains how missing a routine kidney test could harm diabetes ...
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Research into the structure of the kidney glomerulus – making it count
Micron, 2012The renal glomerulus and its components have been intensively studied using microscopy - both light and electron - for decades and much has been learnt about their role in the pathogenesis of chronic kidney diseases such as diabetic nephropathy. In order to get more than purely qualitative information from the images, stereological tools have been ...
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Expression of a thyroglobulin (Tg) variant in mouse kidney glomerulus
Biochemical and Biophysical Research Communications, 2009Thyroglobulin (Tg) is an essential substrate for thyroid hormone biosynthesis whose production is primarily limited to the thyroid follicular cell. We have previously identified an approximately 1.2 kb fragment of Tg mRNA in cultured mouse mesangial cells, and in the present study provide evidence showing that this transcript is transcribed and ...
Huhehasi, Wu +14 more
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[Repartition of the kidney cortex glomerulus in rats].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1979This paper presents the repartition of 989 glomeruli in 8 parallel concentric renal cortex zones, by projecting on a calibrated screen rat kidney slices photographies. The glomerular density increases regularly from the outside to the middle cortical zones and then decreases to the deepest juxtamedullary zones.
J, Cambar, J, Sauerl
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Angiotensin II and the glomerulus: Focus on diabetic kidney disease
Current Hypertension Reports, 2003The renin-angiotensin system plays a key role in the progression of kidney disease, in addition to its well-described role in the maintenance of extracellular fluid volume and blood pressure. Recent studies have shown that blockade of the renin-angiotensin system at the level of the angiotensin II type 1 receptor can have important effects on ...
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Purinergic Receptors in the Glomerulus and Vasculature of the Kidney
2003Publisher Summary This chapter summarizes observations in the area of purinergic control of renal microvascular and glomerular function and highlights important questions that remain to be resolved. It focuses on new developments made related to intrarenal P2 receptors; however, some attention is directed toward observations related to P1 or ...
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A novel Hessian based algorithm for rat kidney glomerulus detection in 3D MRI
Medical Imaging, 2015Min Zhang, Teresa Wu, K. Bennett
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Onconephrology: The intersections between the kidney and cancer
Ca-A Cancer Journal for Clinicians, 2021, Kenar D Jhaveri, Mark A Perazella
exaly
[Autoantibodies against podocytes of the kidney glomerulus].
Immunitat und Infektion, 1995Novel autoantibodies are described which react with renal podocytes. These antibodies were found in 9 patients (2 with renal disease, 2 with liver disease, 2 with rheumatic disease, 1 with achalasia, 1 with carcinoma of the pancreas and 1 with anemia).
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