Results 131 to 140 of about 310,689 (297)

Factors Associated with Recovery of Renal Function following Radical Nephrectomy for Kidney Neoplasms. [PDF]

Clin J Am Soc Nephrol, 2016
Zabor EC, Furberg H, Mashni J, Lee B, Jaimes EA, Russo P.   +5 more
europepmc   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Real‐world study on the characteristics, post‐nephrectomy journey, and outcomes of patients with early‐stage renal cell carcinoma based on risk groups

Cancer Medicine
Objectives To examine real‐world characteristics, journey, and outcomes among patients with locoregional, nonmetastatic renal cell carcinoma (RCC). Methods A retrospective analysis of medical records from the ConcertAI Oncology Dataset was performed on ...
Jose A. Karam, Rituparna Bhattacharya, Adesuwa Ogbomo, Santosh Gautam, Rebekah Yu, Murali Sundaram, Kentaro Imai, Jatin Chhabra, Naomi B. Haas   +8 more
doaj   +1 more source

Spatiotemporal Sequential Delivery of Chidamide Regulates Macrophage Reprogramming in Lymphoma Microenvironment Through HDACs‐STAT3 Pathway

Advanced Science, EarlyView.
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai, Shuo Wang, Xiaotong Peng, Kunpeng Wu, Mengyao Wu, Zhaoning Lu, Haoshu Zhong, Xiaohan Qian, Shuiyi Tan, Hui Yang, Tanlezi Sun, Jing Wang, Jie Zhang, Hua Jiang, Yin Tong, Tong Chen   +15 more
wiley   +1 more source

Síndrome de Wünderlich: presentación de un caso y revisión de la bibliografía Wünderlich syndrome: case presentation and literature review

Revista Colombiana de Cirugía, 2009
Introducción. La hemorragia renal espontánea, o síndrome de Wünderlich, es una afección de presentación rara que, dada la situación urgente y, a veces, vital que plantea, es de gran importancia.
Rafael Pinilla, Sarah López, Juan Carlos Quintana, Ahmed Al-Ezzi Al- Malahi   +3 more
doaj  

Registry of Post-Kidney Transplant Neoplasms in a Large Colombian Cohort with 30 Years of Follow-up

Contexto: el trasplante renal (TxR) es la mejor alternativa de terapia de reemplazo renal (TRR) para pacientes con enfermedad renal crónica (ERC) estadio 5; sin embargo, conlleva un mayor riesgo de desarrollar neoplasias, las cuales representan la ...
Rodelo-Ceballos, Joaquín Roberto, Páez Angarita, Camilo Andrés, Gutiérrez Montoya, Jorge Iván, Henao Sierra, Jorge Enrique, López, Eduardo, Tobón Pereira, Juan Carlos, Velásquez Ospina, Álvaro, Arbeláez Gómez, Mario, Mejía Vélez, Gonzalo, García García, Álvaro, Arango Acosta, Jorge Luis   +10 more
core   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Complete response of metastatic renal cancer with dendritic cell vaccine

International Brazilian Journal of Urology, 2003
INTRODUCTION: We report a case of metastatic renal cell carcinoma that presented involution following therapy with dendritic cells. CASE REPORT: Male, 51-year old patient underwent left radical nephrectomy in September 1999 due to renal cell carcinoma ...
Dall'Oglio Marcos, Srougi Miguel, Barbuto José A.M.   +2 more
doaj  

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Value of the diffusion-weighted MRI in the differential diagnostics of malignant and benign kidney neoplasms - our clinical experience. [PDF]

Pol J Radiol, 2014
Mytsyk Y, Borys Y, Komnatska I, Dutka I, Shatynska-Mytsyk I.   +4 more
europepmc   +1 more source