Results 271 to 280 of about 1,636,249 (373)

Malignant solitary fibrous tumor of the kidney with extracapsular extension beyond the renal capsule: An extremely rare Uro-oncological surgical case and diagnostic challenge. [PDF]

Urol Case Rep
Naravejsakul K.
europepmc   +1 more source

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

Advanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo, Leonardo Barzaghi, Yuan Shen, Edoardo Bellini, Emanuele Martini, Serena Magni, Sara Barozzi, Fabrizio Orsenigo, Dario Parazzoli, Galina V. Beznoussenko, Jasmin Di Franco, Fabian Krautgasser, Jasmin Kaivola, Mario Cinquanta, Alessandro Lazzarin, Sara Sigismund, Johanna Ivaska, Roberto Cerbino, Giorgio Scita   +18 more
wiley   +1 more source

Challenges in diagnosing renal squamous cell carcinoma: a case report with emphasis on histopathology. [PDF]

Pan Afr Med J
Tekulwar P, Gadkari P.
europepmc   +1 more source

Procyanidin Capsules Combat ALF by Restoring Mitochondrial Homeostasis and Inhibiting Necroptosis via the PGAM5/DRP1/PINK1 Pathway

Advanced Science, EarlyView.
A biomimetic self‐assembly strategy, Procyanidin Capsules (PC‐Ca), has been developed, which has great stability, bioavailability, and liver‐targeting efficacy and modulates the KEAP1‐NRF2 axis to inhibit ROS formation and necroptosis, regulate mitochondrial homeostasis through the PGAM5/DRP1/PINK1 signaling pathway in thioacetamide (TAA)‐induced ALF ...
Qing Shi, Minmin Wu, Jinwei Zhong, Chao Chen, Zhuang Huang, Jingxuan Peng, Dong Yang, Xingjie Zan, Zhengfei Wang   +8 more
wiley   +1 more source

Life after radical cystectomy: A mixed-methods targeted review of patient-reported quality of life following bladder removal. [PDF]

BJUI Compass
Griebsch I, Juul K, Bottomley A, Sherafat-Kazemzadeh R, Pemment J, Brooks T, Adiutori R, Bothorel S.   +7 more
europepmc   +1 more source

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source

Chromogranin A-Associated Tubulopathy in a Patient With Neuroendocrine Tumor. [PDF]

Cureus
Sanborn M, Maity A, Limmonick V, Siddiqui A, Salvatore S, McHugh T.   +5 more
europepmc   +1 more source

Local and Systemic Effects of Chronic Intracavernous Injection of Papaverine, Prostaglandine E1 and Saline in Primates [PDF]

, 1989
Aboseif, Sherif R., Bosch, Ruud J. L. H., Breza, J., Bénard, Francois, Lue, Tom F., Stackl, W., Stief, Christian Georg, Tanagho, Emil A.   +7 more
core  

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Case Report: Metastatic renal giant-cell sarcoma in an African pygmy hedgehog (<i>Atelerix albiventris</i>). [PDF]

Front Vet Sci
Díaz-Santana P, Déniz-Marrero J, Gola C, Suárez-Bonnet A.   +3 more
europepmc   +1 more source