Results 41 to 50 of about 63,751 (265)

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

open access: yesAdvanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu   +13 more
wiley   +1 more source

Spontaneous renal pelvis perforation in a single kidney child

open access: yesThe Turkish Journal of Pediatrics
Background. Spontaneous renal pelvis perforation is a rare but serious condition, often associated with urinary obstruction, infection, or increased intrapelvic pressure.
Dilara Beşli Çelik   +5 more
doaj   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li   +13 more
wiley   +1 more source

Mature cystic teratoma of renal pelvis: An unusual presentation at an uncommon site

open access: yesJournal of Indian Association of Pediatric Surgeons, 2019
Teratoma of the kidney is uncommon. We report a case of a young boy with a large, right-sided retroperitoneal cyst suspected as lymphangioma causing hydronephrosis. His renal pelvis was dilated, containing purulent fluid, and a nephrectomy was performed.
Bhuvanagiri Srihari Balaji   +1 more
doaj   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

open access: yesAdvanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin   +13 more
wiley   +1 more source

Renal pelvis cancer with initial symptoms of malignant gastric outlet obstruction

open access: yesIJU Case Reports, 2023
Introduction Gastric outlet obstruction caused by upper tract urothelial carcinoma is rare. Case presentation A 78‐year‐old man presented to the hospital with nausea and vomiting. No hematuria was observed.
Nao Iwamoto   +5 more
doaj   +1 more source

Gephyrin Neurological Autoimmunity

open access: yesAnnals of Neurology, EarlyView.
Gephyrin is a postsynaptic scaffold protein essential for inhibitory neurotransmission. Gephyrin‐immunoglobulin G (IgG) was reported, decades ago, in a single case of paraneoplastic stiff‐person‐like syndrome, but its broader clinical relevance remains unknown.
Maria Chiara Pantuliano   +10 more
wiley   +1 more source

Radical Nephrectomy Following Prior Cryoablation for Renal Cell Carcinoma: A Case Report and Literature Review

open access: yesIJU Case Reports
Introduction Small renal masses account for 48%–66% of renal cell carcinoma diagnoses, influencing management decisions for low‐stage kidney disease.
Spyridon Mitsios   +7 more
doaj   +1 more source

Mucinous adenocarcinoma of the renal pelvis with adenocarcinoma in situ of the ureter

open access: yesUrology Annals, 2011
Primary epithelial tumor of the renal pelvis is rare, and adenocarcinomas account for less than 1% of malignancies arising from the epithelium of the renal pelvis.
Vandana Raphael   +3 more
doaj   +1 more source

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