Results 71 to 80 of about 114,709 (308)

Harnessing Hydrogen Cyanide (HCN): Responsive Chemical Tools for Delivering an Emerging Gasotransmitter

open access: yesAngewandte Chemie, EarlyView.
HCN is an important biological mediator, joining NO, CO, and H2S as a regulatory gasotransmitter. This report outlines the design, development, and application of responsive, activatable, and tunable HCN donors. In‐solution kinetics and selectivity data, as well as demonstration of HCN delivery in live cell environments, support the effectiveness of ...
Michael D. Pluth
wiley   +2 more sources

Association between plasma cadmium and renal stone prevalence in adults in rural areas of Guangxi, China: a case–control study

open access: yesBMC Nephrology, 2022
Background Kidney stones have become a worldwide public health problem. The purpose of this research is to study the relationship between plasma cadmium level and the prevalence of kidney stones in an adult population. Methods The data of this study were
You Li   +11 more
doaj   +1 more source

Therapy modifies cystine kidney stones at the macroscopic scale. Do such alterations exist at the mesoscopic and nanometre scale? [PDF]

open access: yes, 2014
International audienceWith an incidence of 1:7000 births, cystinuria, the most frequent cause of stone formation among genetic diseases, represents a major medical problem.
Dominique Bazin   +5 more
core   +3 more sources

Risk factors of kidney stone disease: a cross-sectional study in the southeast of Iran [PDF]

open access: gold, 2021
Parvin Khalili   +7 more
openalex   +1 more source

Cancer Biology of GSPT1: Mechanisms and Targeted Therapy Opportunities of Molecular Glue Degraders

open access: yesAdvanced Science, EarlyView.
This review systemically summarizes the structure, expression, regulatory networks, and isoform‐specific signaling of GSPT1 in cancers. According to the integration of GSPT1 targeted therapies, current challenges of GSPT1 targeted therapies are further analyzed, and provide therapeutic opportunities for the application of GSPT1 degraders in precision ...
Qiqi Lin   +8 more
wiley   +1 more source

Immunometabolic Rewiring of Dendritic Cells to Overcome Glutamine‐Driven Immune Suppression in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
T26 is an immunometabolic prodrug that modulates colorectal cancer cells. It blocks glutamine metabolism and enhances STING signaling, which promotes the release of reprogrammed extracellular vesicles. These vesicles drive dendritic cell maturation and CD8⁺ T cell activation, thereby strengthening antitumor immunity and improving the effectiveness of ...
Bingjie Zhang   +13 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

open access: yes, 1985
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1237/thumbnail ...

core   +1 more source

Guideline for the Extraction of Extracellular Vesicles From Edible Plants, Fungi and Bacteria

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
ABSTRACT Extracellular vesicles (EVs) have emerged as a type of bioactive component discovered in foods and exhibit excellent functions. This guideline presents a comprehensive operational guideline designed to facilitate the efficient extraction of EVs from edible plant, fungi and bacteria. Beginning with a foundational overview of EVs, this guideline
Luyuan Ni, Yue Zou, Zhenzhu Zhu
wiley   +1 more source

Association between triglyceride-glucose index and nephrolithiasis among the elderly in Amirkola: A cross-sectional population-based study [PDF]

open access: yesCaspian Journal of Internal Medicine
Background: Kidney stones are a condition that is prevalent in the geriatric group and significantly impairs their quality of life. The formation of stones may be associated with insulin resistance, which can be measured using the triglyceride-glucose ...
Parsa Aghajani   +3 more
doaj  

When is choice a good thing?: An experimental study of the impact of choice on patient outcomes [PDF]

open access: yes, 2008
The official published version can be obtained from the link below - Copyright @ Taylor & FrancisAlthough policy emphasises the benefits of choice, an increasing body of work points to times when choice may not always have positive consequences.
Barnett, J, Daniells, E, Ogden, J
core   +2 more sources

Home - About - Disclaimer - Privacy