Results 311 to 320 of about 2,234,350 (412)

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, EarlyView.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

Effects of the pretransplant obesity on kidney transplant outcomes in Korea: a nationwide cohort study. [PDF]

BMC Nephrol
Cho EY, Jeon YH, Huh KH, Hwang SD, Min S, Yang J, Kim MS, Seo YJ, Lim JH, Jung HY, Choi JY, Park SH, Kim YL, Cho JH, Kim CD, Korean Organ Transplantation Registry Study Group.   +15 more
europepmc   +1 more source

THE CADAVER KIDNEY TRANSPLANTATION PROGRAMME OF MILANO IMMUNOLOGICAL REPORT

, 1977
G. Sirchia, F. Mercuriali, M. Scalamogna, V. Rosso Di San Secondo, C. Pizzi, Francesca Poli   +5 more
openalex   +1 more source

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Diabetes Mellitus in Kidney Transplant Recipients and New Hypoglycemic Agent Options. [PDF]

Int J Mol Sci
Bartoli G, Dello Strologo A, Arena M, Ceravolo MJ, Mitterhofer AP, Pesce F, Grandaliano G.   +6 more
europepmc   +1 more source

CADAVERIC KIDNEY TRANSPLANTATION IN A PATIENT WITH DONOR-SPECIFIC ANTILEUKOCYTE CYTOTOXIC ANTIBODIES

, 1971
Ramon Patel, Richard E. Wilson, A G Birtsch, John P. Merrill, Joseph E. Murray, G Busch   +5 more
openalex   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Pharmacogenetics association with long-term clinical evolution in a kidney transplant patients cohort. [PDF]

Curr Res Pharmacol Drug Discov
Sendra L, Olivera-Pasquini GG, Zucchet EG, Genvigir FDV, Beneyto MI, Hernández-Jaras J, Herrero MJ, Aliño SF.   +7 more
europepmc   +1 more source

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

Advanced Science, EarlyView.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li, Yuqin Long, Yunxi Zhu, Jiahui Gu, Ping Zhou, Changhong Miao   +5 more
wiley   +1 more source