Results 81 to 90 of about 2,033,277 (389)
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim +8 more
wiley +1 more source
Initial Experience with Laparoscopic Nephrectomy at Services Hospital Lahore
Proceedings, 2020 Introduction: Nephrectomy means removal of kidney. Laparoscopic nephrectomy is an effective way to remove a diseased or cancerous kidney. Nephrectomy is performed to treat malignant or benign tumors of the kidney and symptomatic non functioning kidney ...
Muhammad Farooq +4 more
doaj +1 more source
MicroRNAs in kidney transplantation [PDF]
Nephrology Dialysis Transplantation, 2014 The discovery of novel classes of non-coding RNAs (ncRNAs) has revolutionized medicine. Long thought to be a mere cellular housekeeper, surprising functions have recently been uncovered. MicroRNAs (miRNAs), are a representative of the class of short ncRNAs, play a fundamental role in the control of DNA and protein biosynthesis and activity as well as ...
J. Wilflingseder +6 more
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto +2 more
wiley +1 more source
Therapeutic application of regeneration-associated cells: a novel source of regenerative medicine
Stem Cell Research & Therapy, 2023 Chronic diseases with comorbidities or associated risk factors may impair the function of regenerative cells and the regenerative microenvironment. Following this consideration, the vasculogenic conditioning culture (VCC) method was developed to boost ...
Amankeldi A. Salybekov +3 more
doaj +1 more source
Optimal Kidney Exchange with Immunosuppressants [PDF]
arXiv, 2021 Algorithms for exchange of kidneys is one of the key successful applications in market design, artificial intelligence, and operations research. Potent immunosuppressant drugs suppress the body's ability to reject a transplanted organ up to the point that a transplant across blood- or tissue-type incompatibility becomes possible.
arxiv
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
An economic assessment of contemporary kidney transplant practice
American Journal of Transplantation, 2018 Kidney transplantation is the optimal therapy for end‐stage renal disease, prolonging survival and reducing spending. Prior economic analyses of kidney transplantation, using Markov models, have generally assumed compatible, low‐risk donors. The economic
D. Axelrod +8 more
semanticscholar +1 more source
Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche
Advanced Healthcare Materials, EarlyView.Hypoxia is a key factor in bone marrow physiology and hematopoietic stem cell behavior. Lower oxygen tension influences the secretion of vasculature‐derived hematopoietic regulatory factors and alters hematopoietic cell behavior in a conditioned medium hydrogel model of bone marrow. Cyclosporin A is used to mitigate normoxic stress during hematopoietic
Gunnar B. Thompson +3 more
wiley +1 more source