Results 81 to 90 of about 2,234,350 (412)

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Utility of POPVESL scoring system in the management of renal pseudoaneurysm: a retrospective study

African Journal of Urology, 2023
Background We intended to assess the role of POPVESL scoring system in managing renal pseudoaneurysm at our institute which is a referral center in this region.
Shashank Singh, Sajad Ahmad Para, Mohammad Saleem Wani, Faiz Manzar, Manjul Kumar   +4 more
doaj   +1 more source

Glecaprevir/Pibrentasvir Treatment in Liver or Kidney Transplant Patients With Hepatitis C Virus Infection

Hepatology, 2018
Well‐tolerated, ribavirin‐free, pangenotypic hepatitis C virus (HCV) treatments for transplant recipients remain a high priority. Once‐daily glecaprevir/pibrentasvir demonstrates high rates of sustained virologic response at 12 weeks posttreatment (SVR12)
N. Reau, P. Kwo, S. Rhee, Robert S. Brown, K. Agarwal, P. Angus, E. Gane, J. Kao, P. Mantry, D. Mutimer, K. Reddy, T. Tran, Yiran B. Hu, A. Gulati, Preethi Krishnan, E. Dumas, A. Porcalla, N. Shulman, Wei Liu, S. Samanta, R. Trinh, X. Forns   +21 more
semanticscholar   +1 more source

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

Advanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na, Yubeen Park, Hyun Lee, Song Hee Kim, Seojoon Bang, Hyeong Seok Kang, Chan Ho Moon, Ju Yeong Gwon, Jong Hwa Seo, Min‐Ho Kang, Soo‐Hong Lee, Gi Doo Cha, Wooram Park, Heemin Kang, Jung‐Hoon Park, Hyun‐Do Jung   +15 more
wiley   +1 more source

Those who Give: Art and Gail Pasquarella Support Jefferson Transplant Institute [PDF]

, 2013
Art Pasquarella is a donor in every sense of the word. He gave a kidney as a living donor to one of his brothers. He gives his time as a volunteer for the National Kidney Foundation.

core   +1 more source

Association Between Declined Offers of Deceased Donor Kidney Allograft and Outcomes in Kidney Transplant Candidates

JAMA Network Open, 2019
Key Points Question What are the outcomes for wait-listed kidney transplant candidates after a transplant center’s refusal to accept a deceased donor kidney offer on their behalf?
S. Husain, Kristen L. King, S. Pastan, R. Patzer, D. Cohen, J. Radhakrishnan, S. Mohan   +6 more
semanticscholar   +1 more source

MicroRNAs in kidney transplantation [PDF]

Nephrology Dialysis Transplantation, 2014
The discovery of novel classes of non-coding RNAs (ncRNAs) has revolutionized medicine. Long thought to be a mere cellular housekeeper, surprising functions have recently been uncovered. MicroRNAs (miRNAs), are a representative of the class of short ncRNAs, play a fundamental role in the control of DNA and protein biosynthesis and activity as well as ...
J. Wilflingseder, R. Reindl-Schwaighofer, J. Sunzenauer, A. Kainz, A. Heinzel, B. Mayer, R. Oberbauer   +6 more
openaire   +3 more sources

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source

Combining Sensitive Crossmatch Assays With Donor/Recipient Human Leukocyte Antigen Eplet Matching Predicts Living-Donor Kidney Transplant Outcome

Kidney International Reports, 2018
Introduction: Despite the different assays available for immune-risk stratification before living-donor kidney transplantation (LDKT), the precise type and number of tests to perform remain uncertain. Methods: In a cohort of 330 consecutive LDKT patients,
Maria Meneghini, Edoardo Melilli, Jaume Martorell, Ignacio Revuelta, Elisabet Rigol-Monzó, Anna Manonelles, Nuria Montero, David Cucchiari, Fritz Diekmann, Josep M. Cruzado, Salvador Gil-Vernet, Josep M. Grinyó, Oriol Bestard   +12 more
doaj   +1 more source

Does early removal of Foley’s catheter have any influence on infection of recipient post renal transplantation? Is it safe? A randomized clinical trial [PDF]

Journal of Nephropathology, 2018
Background: Kidney transplant is a fair option for treatment of a chronic renal failure. Although the outcome and results of kidney transplant are good, it may be associated with some complications. One of the important complications is urinary infection.
Afshar Zomorrodi, Farzad Kakei, Amin Bagheri, Sahar Zomorrodi, Mohsen Mohammadrahimi   +4 more
doaj   +1 more source