Results 81 to 90 of about 828,864 (314)

Development of a Disease Activity Index for the Assessment of VEXAS Syndrome (VEXAS‐DAI)

Arthritis Care &Research, EarlyView.
Objective Vacuoles, E1 enzyme, X‐linked, autoinflammatory, somatic syndrome (VEXAS) syndrome is characterized by a complex spectrum of inflammatory and hematologic manifestations. Clinical research to identify effective therapies is urgently needed but is hindered by the lack of validated outcome measures.
Kevin Byram, Heřman Mann, Danielle Hammond, Onima Chowdhury, Sinisa Savic, Yohei Kirino, Carmelo Gurnari, Maël Heiblig, Thibault Comont, Arsène Mekinian, Mrinal M. Patnaik, Lachelle D. Weeks, Gary Ho, Adam Al‐Hakim, Scott Goldberg, Marcela A. Ferrada, Sophie Georgin‐Lavialle, Peter C. Grayson, Emma M. Groarke, Bhavisha Patel, Megan Sullivan, Sarah A. Buckley, Bryan G. Harder, Raman Garcha, David B. Beck, Matthew J. Koster   +25 more
wiley   +1 more source

The cost of implementing UK guidelines for the management of chronic kidney disease [PDF]

, 2007
Background. Chronic kidney disease (CKD) is a major public health problem. In the UK, guidelines have been developed to facilitate case identification and management.
B. Klebe, Stevens, PE, H. Hobbs, Lamb, EJ, Cooley, R, Hobbs, Helen, Irving, J, John, Ian, Hobbs, H, D. J. O'Donoghue, Farmer, CKT, J. New, Klebe, Bernhard, Middleton, R, S. de Lusignan, Klebe, B, Middleton, Rachel, J. Irving, O'Donoghue, DJ, John, I, R. Middleton, I. John, Stevens, Paul E., P. E. Stevens, New, John, Cooley, Roger, Lamb, Edmund J., R. Cooley, O'Donoghue, Donal J., Farmer, Chris, de Lusignan, S, New, J, Irving, Jean, de Lusignan, Simon, C. K.T. Farmer, E. J. Lamb   +35 more
core   +2 more sources

Short-term clinical outcomes of kidney paired donation in living donor kidney transplants: a retrospective study

Journal of the Pakistan Medical Association
Objective: To evaluate short-term outcomes and patient survival among kidney paired donation cases in living donor kidney transplants. Method: The retrospective, observational study was conducted in December 2024 at the Department of Kidney ...
Asad Bashir, Nasrum Minallah, Fiaz Ahmad Touqeer, Zia Ul Haq Akram, Ali Asad , Salman Jamil   +5 more
doaj   +1 more source

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

Arthritis Care &Research, Accepted Article.
OBJECTIVE Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non‐cardiac surgery. METHODS We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including ...
Ali Yazdanyar, Joshua Baker, Katherine D Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

Reference values and physiological characterization of a specific isolated pig kidney perfusion model [PDF]

, 2007
Background: Models of isolated and perfused kidneys are used to study the effects of drugs, hazardous or toxic substances on renal functions. Since physiological and morphological parameters of small laboratory animal kidneys are difficult to compare to ...
Unger Volker, David A Groneberg, Fischer, Axel, Unger, Volker, Groneberg, Jan David Alexander, Groneberg David A, Volker Unger, Grosse-Siestrup Christian, Fehrenberg Claudia, Meissler, Michael, Axel Fischer, Christian Grosse-Siestrup, Fischer Axel, Meissler Michael, Michael Meissler, Grosse-Siestrup, Christian, Fehrenberg, Claudia, Claudia Fehrenberg   +17 more
core   +1 more source

Wight Loss Challenges in Achieving Transplant Eligibility in Patients with Kidney Failure:A Qualitative Study

, 2022
Rationale & Objective: Patients with kidney failure need kidney replacement therapy to maximize survival. Kidney transplant is a superior mode of kidney replacement therapy for most individuals with kidney failure. Patients with obesity often are not
Hansen, D, Konradsen, H,, Freeman, J, Konradsen, Hanne, Lindhard, Kristine, Lindhard, K, Freeman, Johanne, Hansen, Ditte   +7 more
core   +1 more source

Non-oliguric acute renal failure secondary to a potentially lethal dose of caffeine with acute intoxication: a case report

BMC Nephrology
Background Recently, the incidence of caffeine intoxication has been on an upward trend, with severe outcomes. However, acute kidney injury (AKI) resulting from renal pathologies secondary to caffeine intoxication is rare, and the pathophysiological ...
Ayaka Mitomo, Kunihiro Ishioka, Mitsuru Yanai, Takayasu Ohtake, Sumi Hidaka, Shuzo Kobayashi   +5 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Bioinspired Hydrogels with Broadly Programmable Mechanics for Soft‐Tissue Interfaces

Advanced Functional Materials, EarlyView.
Sea cucumber‐inspired gelatin hydrogels are formed by directional freezing and mechanically programmed through subsequent ionic treatment. Multiscale characterization and modeling link ion‐regulated chain interactions to directional load transfer within the aligned hierarchical architecture.
Youchao Teng, TzuChun Chung, Katpady Akhil Tantry, Siyu Wu, Jing Tian, Yunqi Cui, Lanyu Li, Yongzan Zhou, Zhilei Zhang, Zhe Su, Gaili Cao, Kun‐Wei Yeh, Ruipeng Li, Xianghui Xiao, Adam F. G. Leontowich, Yuan‐Yu Hsueh, Zhao Pan, Kam C. Tam, Badri Narayanan, Song Li, Yimin. A. Wu   +20 more
wiley   +1 more source

Lessons Learned About the Education Needs of Kidney Transplant Recipients: A Mixed-Method Study

Canadian Journal of Kidney Health and Disease
Background: Much of the literature on kidney transplant education focuses on educating recipients prior to transplant or in the early postoperative period. It is unknown whether the information provided is meaningful to patients or whether the importance
Michelle L. Gabriel, Lucy Chen, Sharon Lee, Jenny Accettura, Emily E. Campbell, Melanie Dissanayake, Teresa J. Valenzano-Hacker, Michelle Nash, Lindita Rapi, Niki Dacouris, Weiqiu Yuan, Tiffany Thai   +11 more
doaj   +1 more source