Results 241 to 250 of about 273,215 (316)

Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series

British Journal of Clinical Pharmacology, EarlyView.
Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen, Aurelia H. M. de Vries Schultink, Bas J. M. Peters, Dieuwertje Ruigrok, Rob H. J. Schönwetter, Esther V. Uijtendaal, Maaike A. Sikma   +6 more
wiley   +1 more source

Associated Factors to Nonadherence to Routine Appointments after Kidney Transplantation: The ADHERE Brazil Study. [PDF]

Clin Transplant
Karlburger RL, de Pinho JHS, Basile Colugnati FA, Denhaerynck K, Medina JOP, Veras de Sandes-Freitas T, De Geest S, Sanders-Pinheiro H, ADHERE BRAZIL Study Team.   +8 more
europepmc   +1 more source

Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation

Clinical Anatomy, EarlyView.
ABSTRACT Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs).
Lily Mae Miller, Peter Douglas, Julie Glen, Emma Aitken   +3 more
wiley   +1 more source

Chronic kidney disease management in patients with a failing graft: a comparative study with incident non-transplant hemodialysis patients

Renal Failure
Ana Rita Silva, Maria Guedes Marques, Luís Rodrigues, Lídia Santos, Catarina Romãozinho, Francisco Caramelo, Helena Sá, Arnaldo Figueiredo, Rui Alves, Rita Leal   +9 more
doaj   +1 more source

Bibliometric and visual analysis of overlooked fatigue in kidney transplantation: a narrative review. [PDF]

Ann Med Surg (Lond)
Zhu X, Zhu R, He J, Zhang H, Qi H, Chen B, Zhang M, Gou R, Zhu Y, Mu J, Ma S.   +10 more
europepmc   +1 more source

Ethical Issues Involved in Solid Organ Xenotransplantation

Clinical Anatomy, EarlyView.
ABSTRACT Xenotransplantation (specifically, genetically modified pig‐to‐human transplant of organs, tissues, or cells) clinical trials are set to begin in the United States after decades of pre‐clinical studies and recent decedent and compassionate use investigations. This article provides a primer on the key ethical issues attendant with this emerging
Daniel J. Hurst, Chris Bobier, Luz A. Padilla   +2 more
wiley   +1 more source

Potential Role of SGLT-2 Inhibitors in Improving Allograft Function and Reducing Rejection in Kidney Transplantation. [PDF]

Clin Transplant
Demir ME, Helvacı Ö, Yıldırım T, Merhametsiz Ö, Sezer S.   +4 more
europepmc   +1 more source

CD24 is a promising immunotherapeutic target for enhancing efficacy of third‐generation EGFR‐TKIs on EGFR‐mutated lung cancer

Cancer Communications, EarlyView.
Abstract Background Third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) show initial efficacy in EGFR‐mutated lung cancer, but residual disease persists. This study aimed to investigate cluster of differentiation 24 (CD24) as a translational immunotherapeutic target for enhancing third‐generation EGFR‐TKI efficacy.
Jiaqi Liang, Guoshu Bi, Xiaolong Huang, Zhijie Xu, Yiwei Huang, Yunyi Bian, Guangyao Shan, Wei Guo, Yuanliang Yan, Qihai Sui, Xiaodong Yang, Zhencong Chen, Tao Lu, Huan Zhang, Qun Wang, Wei Jiang, Cheng Zhan   +16 more
wiley   +1 more source