Results 241 to 250 of about 2,170,450 (367)

Synthetic Lethal Therapy Based on Dimorphism for Systemic Infection of Drug‐Resistant Candida albicans

Advanced Science, EarlyView.
To tackle the alarming mortality rate linked to Candida albicans infections, a synthetic lethal strategy precisely aimed at the two distinct forms of this fungus: yeast and hyphae is formulated. Ultimately, through the innovative use of macrophage membranes for drug delivery, the effectiveness of this strategy is substantially boosted while ...
Yang Gao, Jiahe Su, Jiawei Yuan, Qinyan Cao, Yue Wu, Yuyang Xiao, Guang Yang, Ruomu Xia, Jingpeng Yang, Yanan Li, Lina Wu, He Huang, Lingtong Meng   +12 more
wiley   +1 more source

Simultaneous Pancreas and Kidney Transplantation in Patients With Type 2 Diabetes Mellitus. [PDF]

Transpl Int
Owen R, Reynard J, Thompson E, Kourounis G, Snowden C, Maillo-Nieto A, Shaw J, Wilson C, White S.   +8 more
europepmc   +1 more source

Pediatric kidney transplantation: a historical review

Pediatric Research, 2017
P. Verghese
semanticscholar   +1 more source

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source

WCN24-388 A STEP TOWARDS BRIDGING THE GENDER GAP IN DECEASED DONOR KIDNEY TRANSPLANTATION

Kidney International Reports
Khushboo Saxena, Vivek Kute, Himanshu Patel, Divyesh Engineer, Subho Banerjee, Hardik Modi, Usha Patel, Ruchir Dave, Nauka Shah, Shivam Shah, Ved Prakash, Vishal Parmar, Jamal Rizvi, Pranjal Modi, Vineet Mishra   +14 more
doaj   +1 more source

Adult Dual Kidney Transplantation Following Dual Renal Endarterectomy: A Case Series. [PDF]

Clin Transplant
Cabrales A, Vyas J, Orlando G, Webb C, Farney AC, Stratta RJ.   +5 more
europepmc   +1 more source

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, EarlyView.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source

Desensitization With Imlifidase: Overcoming Immunological Barriers in Kidney Transplantation. [PDF]

Kidney Med
Hernández-Velasco PJ, Gutiérrez Martínez E, Polanco Fernández N, González Monte ME, González-García C, Mancebo Sierra E, Andrés Belmonte A.   +6 more
europepmc   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Sex differences in cardiac remodeling after kidney transplantation. [PDF]

BMC Nephrol
Rodríguez OO, Carmona-Ruiz HA, Pérez RE, López JC, Mendez CB, Gudiño IIM, López RAG, Orihuela IQ, Sierra RP.   +8 more
europepmc   +1 more source